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NCT04923178 · ClinicalTrials.gov registry record

A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies

A clinical trial of Bladder Cancer and Urothelial Cancer, sponsored by National Cancer Institute (NCI).

Recruiting
Registry status
1,100
Enrollment target
1
Study location

NCT04923178 is a study of Bladder Cancer and Urothelial Cancer that is actively recruiting participants, run by National Cancer Institute (NCI). The registered enrollment target is 1,100 participants, below the 12,747-participant average among 175 other Bladder Cancer trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04923178, a study of Bladder Cancer and Urothelial Cancer, is actively recruiting participants, sponsored by National Cancer Institute (NCI).

RECRUITING
Registry status
1,100 participants
Enrollment target
1
Study location

Study Summary

Background: Tumors in the genitourinary tracts can occur in the kidney, bladder, prostate, and testicles and can have common and rare histologies. Some cancers that occur along the genitourinary (GU) tract are rare. Some GU tumors are so rare that they are not included in treatment studies or tissue banks. This makes it hard for researchers to determine standards of care. Researchers want to learn more about common and rare GU tumors. Objective: To learn more about urinary tract cancers. Eligibility: People ages 18 and older with urinary tract or GU cancer such as bladder, kidney, testicular, prostate, penis, or neuroendocrine cancer. Design: Participants will be screened with questions about their medical history. Their medical records will be reviewed. Participants will have a physical exam. They will give blood and urine samples. They will complete a survey about their family cancer history. Clinical photographs will be taken to document skin lesions. Participants may have imaging scans of their chest, abdomen, and pelvis. They may have a contrast agent injected into their arm. Participants will get recommendations about how to best manage and treat their cancer. They can ask as many questions as they would like. Participants will provide existing tumor samples if available. They may have optional tumor biopsies up to twice a year. For needle biopsies, the biopsy area will be numbed and they will get a sedative. A needle will be inserted through their skin to collect a tumor sample. For skin biopsies, their skin will be numbed. A small circle of skin will be removed. Some blood and tumor samples may be used for genetic tests. Participants will have frequent follow-up visits. If they cannot visit NIH, their home doctor will be contacted. They will be followed on this study for life....

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 1,100 participants
Start Date 2022-10-24
Est. Completion 2042-12-01

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT04923178

The ClinicalTrials.gov registry entry for NCT04923178 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,747-participant average among 175 other Bladder Cancer trials with a reported enrollment target (91% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Bladder Cancer appearing as the primary indexed condition, and to 0 interventions.

NCT04923178 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT04923178 about?

NCT04923178 is a clinical study titled "A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies". Background: Tumors in the genitourinary tracts can occur in the kidney, bladder, prostate, and testicles and can have common and rare histologies. Some cancers that occur along the genitourinary (GU) tract are rare. Some GU tumors are so rare that they are not included in treatment studies or tissu...

What is the current status of trial NCT04923178?

This trial is currently recruiting. The enrollment target is 1,100 participants. The study started on 2022-10-24. Estimated completion is 2042-12-01.

What conditions does trial NCT04923178 study?

This clinical trial studies the following conditions: Bladder Cancer, Urothelial Cancer, Genitourinary Cancer, Urogenital Neoplasms, Urogenital Cancer.

Who is sponsoring clinical trial NCT04923178?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04923178 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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