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NCT04918316 · ClinicalTrials.gov registry record · NA
Initial Correction Keratoconus
A NA study of Keratoconus, sponsored by University of Illinois at Chicago.
- Active
- Registry status
- NA
- Development phase
- 32
- Enrollment target
- 4
- Study locations
NCT04918316: Active NA study of Keratoconus, sponsored by University of Illinois at Chicago.
NCT04918316 is a NA study of Keratoconus that is active but no longer recruiting, run by University of Illinois at Chicago. The registered enrollment target is 32 participants, below the 1,179-participant average among 21 other Keratoconus trials with a reported enrollment target (97% lower). The trial reports 4 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04918316, a NA study of Keratoconus, is active but no longer recruiting, sponsored by University of Illinois at Chicago.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
- 4
- Study locations
Study Summary
Keratoconus is a non-inflammatory, progressive disease in which corneal irregularity increases. As the condition develops, more advanced forms of optical correction are needed to improve vision for patients. Until recently, small diameter corneal gas permeable lenses were considered the primary mode of correction for patients with keratoconus. Now, however, practitioners have multiple options for reducing the optical aberrations caused by keratoconus, including scleral lenses. As of yet, no single option for optical correction has been identified as the preferred mode of correction in terms of overall patient satisfaction with vision, comfort, and ease of use. The order in which various forms of optical correction would be most logically introduced has yet to be determined. This is a study comparing small diameter corneal gas permeable and large diameter scleral lenses in individuals with keratoconus. This study will prospectively compare visual satisfaction and ease of use between corneal gas permeable and scleral lenses for patients with mild to moderate keratoconus.
Primary Outcome
Each study participant will select whether to continue with Lens 1 or Lens 2. The percentage of those who choose a Scleral Lens will be compared to the percentage of participants who select corneal gas permeable lenses.
Conditions Studied
Interventions
- OTHER Corneal gas permeable lens
Study Locations (4)
Illinois
- University of Illinois at Chicago Eye and Ear Infirmary - Chicago
- Illinois Eye Institute - Chicago
Minnesota
- Mayo Clinic - Rochester
Ohio
- The Ohio State University College of Optometry - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2021-07-23 |
| Est. Completion | 2025-09-01 |
| Phase | NA |
What the registry record for NCT04918316 still lists
NCT04918316 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 1,179-participant average among 21 other Keratoconus trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Keratoconus appearing as the primary indexed condition, and to 1 intervention - of which Corneal gas permeable lens is the first listed.
NCT04918316 reports a single indexed study location in Illinois, Minnesota, Ohio.
Frequently Asked Questions
What is clinical trial NCT04918316 about?
NCT04918316 is a clinical study titled "Initial Correction Keratoconus". Keratoconus is a non-inflammatory, progressive disease in which corneal irregularity increases. As the condition develops, more advanced forms of optical correction are needed to improve vision for patients. Until recently, small diameter corneal gas permeable lenses were considered the primary mode...
What is the current status of trial NCT04918316?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 32 participants. The study started on 2021-07-23. Estimated completion is 2025-09-01.
What conditions does trial NCT04918316 study?
This clinical trial studies the following conditions: Keratoconus.
What interventions are being tested in trial NCT04918316?
The interventions under investigation include: Corneal gas permeable lens (OTHER).
Who is sponsoring clinical trial NCT04918316?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04918316 being conducted?
This trial has 4 study locations across Illinois, Minnesota, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Keratoconus
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04918316's enrollment target sits among peer trials
32 21st of 21 higher than 1 of 21 other Keratoconus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Keratoconus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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