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NCT03760432 · ClinicalTrials.gov registry record · NA
Collagen Cross-linking in Keratoconus
A NA study of Keratoconus, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT03760432: Recruiting NA study of Keratoconus, sponsored by Oregon Health and Science University.
NCT03760432 is a NA study of Keratoconus that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 100 participants, below the 1,176-participant average among 21 other Keratoconus trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03760432, a NA study of Keratoconus, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
Optical Coherence Tomography (OCT) devices are non-contact instruments that can measure the depth of scars, other causes of cloudiness of the cornea, and degree of corneal thinning in patients with keratoconus. Laser Custom Corneal Collagen Cross-linking (CXL) significantly decreases corneal aberrations and improves vision. This study will use OCT-guided setting for the lasers used in the corneal smoothing portion of the laser custom CXL procedure to assess the affect on visual outcomes.
Primary Outcome
The primary goal of the trial is to determine the extent of visual improvement after laser custom CXL compared to preoperative measurements. Vision will be checked at various time points, but the primary time point will be 6-months post-procedure.
Conditions Studied
Interventions
- PROCEDURE Laser Custom Corneal Collagen Cross-Linking
Study Locations (1)
Oregon
- Oregon Health & Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2018-06-20 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT03760432 shows while recruiting
NCT03760432 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,176-participant average among 21 other Keratoconus trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Keratoconus appearing as the primary indexed condition, and to 1 intervention - of which Laser Custom Corneal Collagen Cross-Linking is the first listed.
NCT03760432 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT03760432 about?
NCT03760432 is a clinical study titled "Collagen Cross-linking in Keratoconus". Optical Coherence Tomography (OCT) devices are non-contact instruments that can measure the depth of scars, other causes of cloudiness of the cornea, and degree of corneal thinning in patients with keratoconus. Laser Custom Corneal Collagen Cross-linking (CXL) significantly decreases corneal aberrat...
What is the current status of trial NCT03760432?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2018-06-20. Estimated completion is 2027-12.
What conditions does trial NCT03760432 study?
This clinical trial studies the following conditions: Keratoconus.
What interventions are being tested in trial NCT03760432?
The interventions under investigation include: Laser Custom Corneal Collagen Cross-Linking (PROCEDURE).
Who is sponsoring clinical trial NCT03760432?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03760432 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Keratoconus
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03760432's enrollment target sits among peer trials
100 14th of 21 higher than 5 of 21 other Keratoconus trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Keratoconus trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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