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NCT04911608 · ClinicalTrials.gov registry record · NA
Neuroendocrine Changes in Cervical Spinal Manipulation and Mobilization Non-specific Mechanical Neck Pain
A NA study, sponsored by Loma Linda University.
- Completed
- Registry status
- NA
- Development phase
- 36
- Enrollment target
NCT04911608: Completed NA study, sponsored by Loma Linda University.
NCT04911608 is a NA study that has completed, run by Loma Linda University. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04911608, a NA study, has completed, sponsored by Loma Linda University.
- COMPLETED
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
Study Summary
The aim for this graduate student research project is to determine if cervical spinal mobilization releases similar neuropeptides and endogenous hormones as compared to cervical spinal manipulation and a control group. We hypothesized that application of cervical manipulations would result in a neuroendocrine response (SNS- HPA axis). By measuring salivary cortisol, oxytocin and DHEA, it may be possible to provide important information regarding the mechanisms and associations of pain modulation, anti-inflammatory and tissue healing after a biomechanical event.
Primary Outcome
Survey used to assess self-rated disability in patients with neck pain.
Interventions
- OTHER cervical spinal manipulation
- OTHER cervical spinal mobilization
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2021-06-17 |
| Est. Completion | 2023-01-10 |
| Phase | NA |
What the finished NCT04911608 record still lists
NCT04911608 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which cervical spinal manipulation is the first listed.
NCT04911608 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04911608 about?
NCT04911608 is a clinical study titled "Neuroendocrine Changes in Cervical Spinal Manipulation and Mobilization Non-specific Mechanical Neck Pain". The aim for this graduate student research project is to determine if cervical spinal mobilization releases similar neuropeptides and endogenous hormones as compared to cervical spinal manipulation and a control group. We hypothesized that application of cervical manipulations would result in a neur...
What is the current status of trial NCT04911608?
This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2021-06-17. Estimated completion is 2023-01-10.
What interventions are being tested in trial NCT04911608?
The interventions under investigation include: cervical spinal manipulation (OTHER), cervical spinal mobilization (OTHER).
Who is sponsoring clinical trial NCT04911608?
This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04911608's enrollment target sits among peer trials
36 1541st of 2000 higher than 437 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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