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NCT04905914 · ClinicalTrials.gov registry record · Phase 1

Study Of ATRN-119 In Patients With Advanced Solid Tumors

A Phase 1 study of Advanced Solid Tumor, sponsored by Aprea Therapeutics.

Active
Registry status
Phase 1
Development phase
132
Enrollment target
7
Study locations

NCT04905914 is a Phase 1 study of Advanced Solid Tumor that is active but no longer recruiting, run by Aprea Therapeutics. The registered enrollment target is 132 participants, below the 192-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (31% lower). The trial reports 7 study locations across 5 states.

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The verdict

NCT04905914, a Phase 1 study of Advanced Solid Tumor, is active but no longer recruiting, sponsored by Aprea Therapeutics.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
132 participants
Enrollment target
7
Study locations

Study Summary

The purpose of this study is to assess the safety and effectiveness of ATRN-119 through the performance of a Phase 1/2a, open-label, safety, PK, and preliminary efficacy study of oral ATRN-119 in patients with advanced solid tumors.

Conditions Studied

Advanced Solid Tumor

Interventions

  • DRUG ATRN-119

Study Locations (7)

Texas

  • Mary Crowley Cancer Research - Dallas
  • NEXT- Oncology Dallas - Irving
  • NEXT Oncology- San Antonio - San Antonio

Connecticut

  • Yale Cancer Center - New Haven

Ohio

  • University Hospitals, Cleveland Medical Center - Cleveland

Pennsylvania

  • Jordan Center for Gynecologic Oncology at Penn Perelman Center for Advanced Medicine - Philadelphia

Virginia

  • NEXT Oncology- Virginia - Fairfax

Trial Details

FieldValue
Enrollment Target 132 participants
Start Date 2023-01-09
Est. Completion 2028-02
Phase Phase 1

Sponsor

Aprea Therapeutics

9 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04905914

The ClinicalTrials.gov registry entry for NCT04905914 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 132 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 192-participant average among 189 other Advanced Solid Tumor trials with a reported enrollment target (31% lower). The listed sponsor is Aprea Therapeutics, which has 9 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumor appearing as the primary indexed condition, and to 1 intervention - of which ATRN-119 is the first listed.

NCT04905914 reports 7 study locations spanning 5 distinct geographic areas - top geographies include Texas, Connecticut, Ohio.

Frequently Asked Questions

What is clinical trial NCT04905914 about?

NCT04905914 is a clinical study titled "Study Of ATRN-119 In Patients With Advanced Solid Tumors". The purpose of this study is to assess the safety and effectiveness of ATRN-119 through the performance of a Phase 1/2a, open-label, safety, PK, and preliminary efficacy study of oral ATRN-119 in patients with advanced solid tumors.

What is the current status of trial NCT04905914?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 132 participants. The study started on 2023-01-09. Estimated completion is 2028-02.

What conditions does trial NCT04905914 study?

This clinical trial studies the following conditions: Advanced Solid Tumor.

What interventions are being tested in trial NCT04905914?

The interventions under investigation include: ATRN-119 (DRUG).

Who is sponsoring clinical trial NCT04905914?

This trial is sponsored by Aprea Therapeutics, which has 9 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04905914 being conducted?

This trial has 7 study locations across Connecticut, Ohio, Pennsylvania, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.