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NCT04886726 · ClinicalTrials.gov registry record · Phase 1
PTCY Plus uhCG/EGF for Graft Versus Host Disease Prophylaxis
A Phase 1 study of Graft-Versus-Host Disease, sponsored by Henry Ford Health System.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT04886726: Recruiting Phase 1 study of Graft-Versus-Host Disease, sponsored by Henry Ford Health System.
NCT04886726 is a Phase 1 study of Graft-Versus-Host Disease that is actively recruiting participants, run by Henry Ford Health System. The registered enrollment target is 18 participants, below the 82-participant average among 38 other Graft-Versus-Host Disease trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04886726, a Phase 1 study of Graft-Versus-Host Disease, is actively recruiting participants, sponsored by Henry Ford Health System.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
So this a Phase I study with primary objective to determine the feasibility and safety of combining post-transplant cyclophosphamide and urinary-derived human chorionic gonadotropin and epidermal growth factor (uhCG/EGF) as graft versus host disease prophylaxis in stem cell transplant with MMUDs Secondary objectives are to determine the incidence acute and chronic GVHD, progression-free survival , and overall survival
Primary Outcome
The maximum tolerated dose
Conditions Studied
Interventions
- DRUG uhCG/EGF
Study Locations (1)
Michigan
- Henry Ford Hospital - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2021-12-23 |
| Est. Completion | 2028-11-30 |
| Phase | Phase 1 |
What NCT04886726 shows while recruiting
NCT04886726 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 82-participant average among 38 other Graft-Versus-Host Disease trials with a reported enrollment target (78% lower).
The record links to 1 condition, with Graft-Versus-Host Disease appearing as the primary indexed condition, and to 1 intervention - of which uhCG/EGF is the first listed.
NCT04886726 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT04886726 about?
NCT04886726 is a clinical study titled "PTCY Plus uhCG/EGF for Graft Versus Host Disease Prophylaxis". So this a Phase I study with primary objective to determine the feasibility and safety of combining post-transplant cyclophosphamide and urinary-derived human chorionic gonadotropin and epidermal growth factor (uhCG/EGF) as graft versus host disease prophylaxis in stem cell transplant with MMUDs Sec...
What is the current status of trial NCT04886726?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2021-12-23. Estimated completion is 2028-11-30.
What conditions does trial NCT04886726 study?
This clinical trial studies the following conditions: Graft-Versus-Host Disease.
What interventions are being tested in trial NCT04886726?
The interventions under investigation include: uhCG/EGF (DRUG).
Who is sponsoring clinical trial NCT04886726?
This trial is sponsored by Henry Ford Health System, which has 234 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04886726 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Graft-Versus-Host Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04886726's enrollment target sits among peer trials
18 34th of 38 higher than 5 of 38 other Graft-Versus-Host Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Graft-Versus-Host Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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