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NCT04877977 · ClinicalTrials.gov registry record
Long-term Observation of Participants With Mood Disorders
A clinical trial of Depression and Suicide Risk, sponsored by National Institute of Mental Health (NIMH).
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 1
- Study location
NCT04877977: Recruiting study of Depression and Suicide Risk, sponsored by National Institute of Mental Health (NIMH).
NCT04877977 is a study of Depression and Suicide Risk that is actively recruiting participants, run by National Institute of Mental Health (NIMH). The registered enrollment target is 1,000 participants, above the 785-participant average among 679 other Depression trials with a reported enrollment target (27% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04877977, a study of Depression and Suicide Risk, is actively recruiting participants, sponsored by National Institute of Mental Health (NIMH).
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: More than 12,000 people have taken part in research at the Experimental Therapeutics \& Pathophysiology Branch at the National Institute of Mental Health Intramural Program. This has led to advances in the treatment of depression, bipolar disorder, and suicide risk. Researchers want to follow up with this group to see if they continue to have mental health symptoms and receive psychiatric treatments. Objective: To learn the long-term impact of depression, bipolar disorder, and suicide risk. Eligibility: Adults ages 18 and older who signed consent for Protocol 01-M-0254 over a year ago. Design: This study has 2 phases: an online phase and a telephone phase. It has no in-person or face-to-face contact. In Phase 1, participants will fill out online surveys. They will access the surveys through the study website. The questions will focus on their current thoughts and feelings. The surveys will also ask about their current treatments for their mental health symptoms. At the end of the surveys, they will be asked if they would like to take part in Phase 2. If so, they will mark yes. Phase 2 includes a phone interview. They will be contacted by email to schedule the interview. In Phase 2, participants will be asked more in-depth questions about how they are feeling. They will also be asked which psychiatric medicines and treatments they have used since they left NIH. In both phases, participants can skip any questions they do not want to answer. The online surveys will take 30 minutes to complete. The phone interview will last 1-4 hours. The information that participants give in this study may be linked to their other NIH research records.
Primary Outcome
Rating of depression without assessment of suicidal ideation
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2021-08-17 |
| Est. Completion | 2028-10-01 |
What NCT04877977 shows while recruiting
NCT04877977 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, above the 785-participant average among 679 other Depression trials with a reported enrollment target (27% higher).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 0 interventions.
NCT04877977 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04877977 about?
NCT04877977 is a clinical study titled "Long-term Observation of Participants With Mood Disorders". Background: More than 12,000 people have taken part in research at the Experimental Therapeutics \& Pathophysiology Branch at the National Institute of Mental Health Intramural Program. This has led to advances in the treatment of depression, bipolar disorder, and suicide risk. Researchers want to ...
What is the current status of trial NCT04877977?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2021-08-17. Estimated completion is 2028-10-01.
What conditions does trial NCT04877977 study?
This clinical trial studies the following conditions: Depression, Suicide Risk.
Who is sponsoring clinical trial NCT04877977?
This trial is sponsored by National Institute of Mental Health (NIMH), which has 343 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04877977 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04877977's enrollment target sits among peer trials
1,000 37th of 679 higher than 639 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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