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NCT04876807 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Effect of an Acidic Formulation of Acalabrutinib (ACP-196), Acidic Beverage, or Grapefruit Juice on the Pharmacokinetics (PK) of ACP-196 Alone and Coadministered With Omeprazole
A Phase 1 study, sponsored by Acerta Pharma.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
NCT04876807: Completed Phase 1 study, sponsored by Acerta Pharma.
NCT04876807 is a Phase 1 study that has completed, run by Acerta Pharma. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04876807, a Phase 1 study, has completed, sponsored by Acerta Pharma.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
Study Summary
This study will evaluate the effect of an acidic formulation of Acalabrutinib (ACP-196), acidic beverage, or grapefruit Juice on the PK of ACP-196 alone and coadministered with omeprazole.
Interventions
- DRUG Omeprazole
- DRUG ACP-196
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2016-01-28 |
| Est. Completion | 2016-03-15 |
| Phase | Phase 1 |
What the finished NCT04876807 record still lists
NCT04876807 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).
The record links to 0 conditions, and to 2 interventions - of which Omeprazole is the first listed.
NCT04876807 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04876807 about?
NCT04876807 is a clinical study titled "A Study to Evaluate the Effect of an Acidic Formulation of Acalabrutinib (ACP-196), Acidic Beverage, or Grapefruit Juice on the Pharmacokinetics (PK) of ACP-196 Alone and Coadministered With Omeprazole". This study will evaluate the effect of an acidic formulation of Acalabrutinib (ACP-196), acidic beverage, or grapefruit Juice on the PK of ACP-196 alone and coadministered with omeprazole.
What is the current status of trial NCT04876807?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2016-01-28. Estimated completion is 2016-03-15.
What interventions are being tested in trial NCT04876807?
The interventions under investigation include: Omeprazole (DRUG), ACP-196 (DRUG).
Who is sponsoring clinical trial NCT04876807?
This trial is sponsored by Acerta Pharma, which has 38 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04876807's enrollment target sits among peer trials
36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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