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NCT04851301 · ClinicalTrials.gov registry record · Phase 1
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
A Phase 1 study of Pain and Virtual Reality, sponsored by University of Maryland, Baltimore.
- Active
- Registry status
- Phase 1
- Development phase
- 259
- Enrollment target
- 1
- Study location
NCT04851301: Active Phase 1 study of Pain and Virtual Reality, sponsored by University of Maryland, Baltimore.
NCT04851301 is a Phase 1 study of Pain and Virtual Reality that is active but no longer recruiting, run by University of Maryland, Baltimore. The registered enrollment target is 259 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (15% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04851301, a Phase 1 study of Pain and Virtual Reality, is active but no longer recruiting, sponsored by University of Maryland, Baltimore.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 259 participants
- Enrollment target
- 1
- Study location
Study Summary
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Primary Outcome
Increments in experimental ischemic pain endurance will be assessed using a timer (minutes of tolerance)
Conditions Studied
Interventions
- OTHER Saline
- OTHER No Intervention
- DRUG Naloxone
- BEHAVIORAL Active Virtual Reality
- BEHAVIORAL sham Virtual Reality
Study Locations (1)
Maryland
- Luana Colloca - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 259 participants |
| Start Date | 2021-11-01 |
| Est. Completion | 2026-11-30 |
| Phase | Phase 1 |
What the registry record for NCT04851301 still lists
NCT04851301 is an interventional study that assigns participants to a tested intervention. The registered 259 participants enrollment target is mid-sized for trials with a published cap, below the 304-participant average among 374 other Pain trials with a reported enrollment target (15% lower).
The record links to 4 conditions, with Pain appearing as the primary indexed condition, and to 5 interventions - of which Saline is the first listed.
NCT04851301 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04851301 about?
NCT04851301 is a clinical study titled "Neural Mechanisms of Immersive Virtual Reality in Chronic Pain". This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
What is the current status of trial NCT04851301?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 259 participants. The study started on 2021-11-01. Estimated completion is 2026-11-30.
What conditions does trial NCT04851301 study?
This clinical trial studies the following conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder.
What interventions are being tested in trial NCT04851301?
The interventions under investigation include: Saline (OTHER), No Intervention (OTHER), Naloxone (DRUG), Active Virtual Reality (BEHAVIORAL), sham Virtual Reality (BEHAVIORAL).
Who is sponsoring clinical trial NCT04851301?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04851301 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04851301's enrollment target sits among peer trials
259 67th of 374 higher than 308 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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