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Invest-CTO PCI Trial
NCT04774913 · View on ClinicalTrials.gov ↗
Study Summary
Following unsuccessful CTO crossing a CTO modification procedure is sometimes performed. CTO PCI registries where plaque modification has been performed in some patients, report this to be safe, and associated with higher success rates at subsequent attempts. It has never been investigated whether a planned investment procedure, with an intention that both the initial and staged completion PCI are of shorter duration, could improve safety and efficacy. The investigators hypothesize that 1. A planned investment procedure in the treatment of CTOs will be associated with improved patient safety 2. A planned investment procedure will be associated with improved cumulative procedure success rates 3. A planned two stage procedure will be associated with improved patient experience
Conditions Studied
Interventions
- PROCEDURE Chronic total occlusion(CTO) percutaneous coronary intervention (PCI)
Study Locations (5)
Other
- Bristol Health — Bristol
- St George´s Hospital — London
New York
- Columbia University Medical Center/ NewYork Presbyterian Hospital — New York
Bergen
- Haukeland University Hospital — Bergen
Glasgow
- Golden Jubilee National Hospital — Glasgow
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2021-12-08 |
| Est. Completion | 2026-10 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04774913
The ClinicalTrials.gov registry entry for NCT04774913 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Haukeland University Hospital, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 4 conditions, with Quality of Life appearing as the primary indexed condition, and to 1 intervention — of which Chronic total occlusion(CTO) percutaneous coronary intervention (PCI) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04774913 reports 5 study locations spanning 4 distinct geographic areas — top geographies include Other, New York, Bergen. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04774913 about?
NCT04774913 is a clinical study titled "Invest-CTO PCI Trial". Following unsuccessful CTO crossing a CTO modification procedure is sometimes performed. CTO PCI registries where plaque modification has been performed in some patients, report this to be safe, and associated with higher success rates at subsequent attempts. It has never been investigated whether ...
What is the current status of trial NCT04774913?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2021-12-08. Estimated completion is 2026-10.
What conditions does trial NCT04774913 study?
This clinical trial studies the following conditions: Quality of Life, Angina Pectoris, Chronic Total Occlusion of Coronary Artery, PROM. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04774913?
The interventions under investigation include: Chronic total occlusion(CTO) percutaneous coronary intervention (PCI) (PROCEDURE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04774913?
This trial is sponsored by Haukeland University Hospital, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04774913 being conducted?
This trial has 5 study locations across New York, Bergen, Glasgow. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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