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NCT04680221 · ClinicalTrials.gov registry record · Phase 4
Stopping Opioid Overuse in Obstetrics to Halt Exposure Trial
A Phase 4 study of Pain, Postoperative and Opioid Use, sponsored by University of Missouri, Kansas City.
- Active
- Registry status
- Phase 4
- Development phase
- 97
- Enrollment target
- 1
- Study location
NCT04680221: Active Phase 4 study of Pain, Postoperative and Opioid Use, sponsored by University of Missouri, Kansas City.
NCT04680221 is a Phase 4 study of Pain, Postoperative and Opioid Use that is active but no longer recruiting, run by University of Missouri, Kansas City. The registered enrollment target is 97 participants, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (64% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04680221, a Phase 4 study of Pain, Postoperative and Opioid Use, is active but no longer recruiting, sponsored by University of Missouri, Kansas City.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 4
- Development phase
- 97 participants
- Enrollment target
- 1
- Study location
Study Summary
As the opioid epidemic continues on, more research is needed on multi-modal approaches to decrease opioid exposure after common procedures. The aim of this study is to investigate the role of a transverses abdominis block using liposome bupivacaine suspension in reducing use of opioid medications through post-operative day 7. The study is a proposed double-blind, randomized controlled trial.
Primary Outcome
Amount of opioid medications taken converted to Morphine Milligram Equivalents
Conditions Studied
Interventions
- DRUG Liposomal bupivacaine
- PROCEDURE TAP block
- DRUG Deposition of saline
Study Locations (1)
Missouri
- Truman Medical Center - Lakewood - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 97 participants |
| Start Date | 2021-03-01 |
| Est. Completion | 2025-06-01 |
| Phase | Phase 4 |
What the registry record for NCT04680221 still lists
NCT04680221 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 97 participants, a relatively small participant target, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (64% lower).
The record links to 2 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 3 interventions - of which Liposomal bupivacaine is the first listed.
NCT04680221 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT04680221 about?
NCT04680221 is a clinical study titled "Stopping Opioid Overuse in Obstetrics to Halt Exposure Trial". As the opioid epidemic continues on, more research is needed on multi-modal approaches to decrease opioid exposure after common procedures. The aim of this study is to investigate the role of a transverses abdominis block using liposome bupivacaine suspension in reducing use of opioid medications th...
What is the current status of trial NCT04680221?
This trial is currently active not recruiting. It is a Phase 4 study. The enrollment target is 97 participants. The study started on 2021-03-01. Estimated completion is 2025-06-01.
What conditions does trial NCT04680221 study?
This clinical trial studies the following conditions: Pain, Postoperative, Opioid Use.
What interventions are being tested in trial NCT04680221?
The interventions under investigation include: Liposomal bupivacaine (DRUG), TAP block (PROCEDURE), Deposition of saline (DRUG).
Who is sponsoring clinical trial NCT04680221?
This trial is sponsored by University of Missouri, Kansas City, which has 33 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04680221 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04680221's enrollment target sits among peer trials
97 49th of 113 higher than 65 of 113 other Pain, Postoperative trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Postoperative trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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