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NCT06280092 · ClinicalTrials.gov registry record · Early Phase 1
Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery
A Early Phase 1 study of Epilepsy, sponsored by Sanjeet S. Grewal.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 5
- Enrollment target
- 1
- Study location
NCT06280092 is a Early Phase 1 study of Epilepsy that is actively recruiting participants, run by Sanjeet S. Grewal. The registered enrollment target is 5 participants, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06280092, a Early Phase 1 study of Epilepsy, is actively recruiting participants, sponsored by Sanjeet S. Grewal.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 5 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is a non-randomized, open label, phase 1 clinical trial to evaluate the fesibility and safety of intrathalamic delivery of MSCs during standard of care DBS surgery for epilepsy. Subjects will be screened at our outpatient clinic and interested qualified subjects will be consented and offered participation in this trial. Once consent has been obtained, patients will undergo a standard preoperative evaluation which includes baseline laboratory values and a high-definition MRI. Patients will then undergo a stereotactic procedure for bilateral thalamic implantation of DBS leads through the ClearPoint® system. After the thalamic target for DBS is identified, cells will be infused directly into the anterior nucleus of the thalamus previous to lead implantation. Patients will be followed in the outpatient setting for up to a year after therapy application. Surgical, clinical, and radiographic data will be obtained during these visits
Conditions Studied
Interventions
- DRUG AMSCs
Study Locations (1)
Florida
- Mayo Clinic - Jacksonville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2024-12-23 |
| Est. Completion | 2026-03 |
| Phase | Early Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06280092
The ClinicalTrials.gov registry entry for NCT06280092 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 952-participant average among 160 other Epilepsy trials with a reported enrollment target (99% lower). The listed sponsor is Sanjeet S. Grewal, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Epilepsy appearing as the primary indexed condition, and to 1 intervention - of which AMSCs is the first listed.
NCT06280092 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.
Frequently Asked Questions
What is clinical trial NCT06280092 about?
NCT06280092 is a clinical study titled "Allogenic Adipose-derived Mesenchymal Stem Cells(AMSCs) for Epilepsy During Deep Brain Stimulation(DBS) Surgery". This study is a non-randomized, open label, phase 1 clinical trial to evaluate the fesibility and safety of intrathalamic delivery of MSCs during standard of care DBS surgery for epilepsy. Subjects will be screened at our outpatient clinic and interested qualified subjects will be consented and off...
What is the current status of trial NCT06280092?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 5 participants. The study started on 2024-12-23. Estimated completion is 2026-03.
What conditions does trial NCT06280092 study?
This clinical trial studies the following conditions: Epilepsy.
What interventions are being tested in trial NCT06280092?
The interventions under investigation include: AMSCs (DRUG).
Who is sponsoring clinical trial NCT06280092?
This trial is sponsored by Sanjeet S. Grewal, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06280092 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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