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NCT04627025 · ClinicalTrials.gov registry record · Phase 3
Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF
A Phase 3 study of Short Bowel Syndrome, sponsored by VectivBio.
- Completed
- Registry status
- Phase 3
- Development phase
- 164
- Enrollment target
- 20
- Study locations
NCT04627025: Completed Phase 3 study of Short Bowel Syndrome, sponsored by VectivBio.
NCT04627025 is a Phase 3 study of Short Bowel Syndrome that has completed, run by VectivBio. The registered enrollment target is 164 participants, roughly in line with the 175-participant average among 17 other Short Bowel Syndrome trials with a reported enrollment target. The trial reports 20 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04627025, a Phase 3 study of Short Bowel Syndrome, has completed, sponsored by VectivBio.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 164 participants
- Enrollment target
- 20
- Study locations
Study Summary
The primary objective of the trial is the confirmation of the efficacy of apraglutide to evaluate the efficacy of weekly subcutaneous apraglutide in reducing parenteral support dependency.
Conditions Studied
Interventions
- DRUG apraglutide
Study Locations (20)
Other
- University Hospital Foundation Favaloro - Buenos Aires
- University Hospital Brussels - Brussels
- University Hospital Brno - Brno
- University Hospital Hradec Kralove - Hradec Králové
- Hospital Novy Jicin - Nový Jičín
- University Hospital Plzen - Pilsen
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
- Cleveland Clinic Foundation - Cleveland
California
- Ronald Reagan UCLA Medical Center - Los Angeles
Florida
- Gastroenterology Group of Naples - Naples
Illinois
- Northwestern University - Chicago
Michigan
- Henry Ford Medical Center - Columbus - Novi
Minnesota
- Mayo Clinic - Rochester
Nebraska
- University of Nebraska Medical Center - Omaha
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 164 participants |
| Start Date | 2021-01-26 |
| Est. Completion | 2024-02-22 |
| Phase | Phase 3 |
What the finished NCT04627025 record still lists
NCT04627025 is an interventional study that assigns participants to a tested intervention. The registered 164 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 175-participant average among 17 other Short Bowel Syndrome trials with a reported enrollment target.
The record links to 1 condition, with Short Bowel Syndrome appearing as the primary indexed condition, and to 1 intervention - of which apraglutide is the first listed.
NCT04627025 names 20 study sites across 14 states, led by Other, Ohio, California.
Frequently Asked Questions
What is clinical trial NCT04627025 about?
NCT04627025 is a clinical study titled "Trial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF". The primary objective of the trial is the confirmation of the efficacy of apraglutide to evaluate the efficacy of weekly subcutaneous apraglutide in reducing parenteral support dependency.
What is the current status of trial NCT04627025?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 164 participants. The study started on 2021-01-26. Estimated completion is 2024-02-22.
What conditions does trial NCT04627025 study?
This clinical trial studies the following conditions: Short Bowel Syndrome.
What interventions are being tested in trial NCT04627025?
The interventions under investigation include: apraglutide (DRUG).
Who is sponsoring clinical trial NCT04627025?
This trial is sponsored by VectivBio, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04627025 being conducted?
This trial has 20 study locations across California, Florida, Illinois, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Short Bowel Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04627025's enrollment target sits among peer trials
164 2nd of 17 the highest of 17 other Short Bowel Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Short Bowel Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS
RECRUITING · Phase 3
-
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS
ACTIVE NOT RECRUITING · Phase 3
-
Evaluation of Long Term Safety and Efficacy of Glepaglutide in Treatment of SBS - Extension Trial
ACTIVE NOT RECRUITING · Phase 3
-
Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.
ACTIVE NOT RECRUITING · Phase 3
-
Safety and Efficacy Study of Teduglutide in Subjects With Short Bowel Syndrome
COMPLETED · Phase 3
-
Long-term Safety and Efficacy Study of Teduglutide in Pediatric Participants With Short Bowel Syndrome (SBS)
COMPLETED · Phase 3
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