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Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS
NCT07197944 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of the present Phase 3 trial is to confirm the efficacy and safety of glepaglutide 10 mg twice weekly in a patient population with SBS-IF and generate additional long-term safety data. Glepaglutide is the International Nonproprietary Name and United States Adopted Name (USAN) for ZP1848.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG Glepaglutide
Study Locations (17)
Other
- Rigshospitalet-Blegdamsvej 9 — Copenhagen
- AP-HP - Hôpital Beaujon — Clichy
- Charité - Universitätsmedizin Berlin — Berlin
- Universitätsklinikum Bonn — Bonn
- Oslo Universitetssykehus HF, Ullevål — Oslo
- Sahlgrenska Universitets sjukhuset — Gothenburg
- Karolinska Universitetssjukhuset Solna — Solna
Madrid
- Hospital General Universitario Gregorio Marañon — Madrid
- Hospital Universitario 12 de Octubre — Madrid
Missouri
- Washington University Center for Advanced Medicine — St Louis
Vienna
- Universitätsklinikum AKH Wien — Vienna
Mecklenburg-Vorpommern
- Universitätsmedizin Rostock — Rostock
Saxony
- Eugastro Klinische Studien GmbH — Leipzig
Lazio
- Fondazione Policlinico Universitario A. Gemelli IRCCS - PPDS — Rome
Gelderland
- Radboud Universitair Medisch Centrum — Nijmegen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2026-02-11 |
| Est. Completion | 2032-02-28 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07197944
The ClinicalTrials.gov registry entry for NCT07197944 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Zealand Pharma, which has 8 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Short Bowel Syndrome appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07197944 reports 17 study locations spanning 10 distinct geographic areas — top geographies include Other, Madrid, Missouri. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07197944 about?
NCT07197944 is a clinical study titled "Efficacy And Safety Evaluation of Glepaglutide in Treatment of SBS". The purpose of the present Phase 3 trial is to confirm the efficacy and safety of glepaglutide 10 mg twice weekly in a patient population with SBS-IF and generate additional long-term safety data. Glepaglutide is the International Nonproprietary Name and United States Adopted Name (USAN) for ZP1848...
What is the current status of trial NCT07197944?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 90 participants. The study started on 2026-02-11. Estimated completion is 2032-02-28.
What conditions does trial NCT07197944 study?
This clinical trial studies the following conditions: Short Bowel Syndrome. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07197944?
The interventions under investigation include: Placebo (OTHER), Glepaglutide (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07197944?
This trial is sponsored by Zealand Pharma, which has 8 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07197944 being conducted?
This trial has 17 study locations across Missouri, Vienna, Mecklenburg-Vorpommern, Saxony, Lazio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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