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NCT04622150 · ClinicalTrials.gov registry record · NA
Effectiveness RCT of Customized Adherence Enhancement
A NA study of Bipolar Disorder, sponsored by Case Western Reserve University.
- Active
- Registry status
- NA
- Development phase
- 190
- Enrollment target
- 3
- Study locations
NCT04622150: Active NA study of Bipolar Disorder, sponsored by Case Western Reserve University.
NCT04622150 is a NA study of Bipolar Disorder that is active but no longer recruiting, run by Case Western Reserve University. The registered enrollment target is 190 participants, below the 332-participant average among 162 other Bipolar Disorder trials with a reported enrollment target (43% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04622150, a NA study of Bipolar Disorder, is active but no longer recruiting, sponsored by Case Western Reserve University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 190 participants
- Enrollment target
- 3
- Study locations
Study Summary
Approximately one in two individuals with bipolar disorder (BD) are non-adherent with medication, often leading to severe and negative consequences. Unfortunately, there is no widely used evidence-based approach to target poor adherence among individuals with BD. Building upon positive efficacy trial results, the proposed project will test the effectiveness of technology-facilitated Customized Adherence Enhancement (CAE) vs. enhanced treatment as usual (eTAU) using a prospective randomized controlled design in public mental health care settings and preferentially enrolling poorly adherent/high-risk individuals with BD. Deliverables include a curriculum-driven adherence enhancement approach that can be implemented in public healthcare settings and which can improve outcomes for the most vulnerable groups of people with BD.
Primary Outcome
The TRQ "past week" item is a subject report of the percentage of prescribed medications not taken within the past week. The minimum score is 0 and the maximum score is 100. A higher score implies poorer treatment adherence.
Conditions Studied
Interventions
- BEHAVIORAL Customized Adherence Enhancement (CAE)
- BEHAVIORAL Enhanced Treatment as Usual (eTAU)
Study Locations (3)
Ohio
- W.O. Walker Center - Cleveland
- MetroHealth Medical Center - Cleveland
- The Nord Center - Lorain
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 190 participants |
| Start Date | 2022-02-01 |
| Est. Completion | 2026-06-01 |
| Phase | NA |
What the registry record for NCT04622150 still lists
NCT04622150 is an interventional study that assigns participants to a tested intervention. The registered 190 participants enrollment target is mid-sized for trials with a published cap, below the 332-participant average among 162 other Bipolar Disorder trials with a reported enrollment target (43% lower).
The record links to 1 condition, with Bipolar Disorder appearing as the primary indexed condition, and to 2 interventions - of which Customized Adherence Enhancement (CAE) is the first listed.
NCT04622150 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT04622150 about?
NCT04622150 is a clinical study titled "Effectiveness RCT of Customized Adherence Enhancement". Approximately one in two individuals with bipolar disorder (BD) are non-adherent with medication, often leading to severe and negative consequences. Unfortunately, there is no widely used evidence-based approach to target poor adherence among individuals with BD. Building upon positive efficacy tria...
What is the current status of trial NCT04622150?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 190 participants. The study started on 2022-02-01. Estimated completion is 2026-06-01.
What conditions does trial NCT04622150 study?
This clinical trial studies the following conditions: Bipolar Disorder.
What interventions are being tested in trial NCT04622150?
The interventions under investigation include: Customized Adherence Enhancement (CAE) (BEHAVIORAL), Enhanced Treatment as Usual (eTAU) (BEHAVIORAL).
Who is sponsoring clinical trial NCT04622150?
This trial is sponsored by Case Western Reserve University, which has 141 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04622150 being conducted?
This trial has 3 study locations across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Bipolar Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04622150's enrollment target sits among peer trials
190 38th of 162 higher than 124 of 162 other Bipolar Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Bipolar Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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