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NCT04517565 · ClinicalTrials.gov registry record · NA
Longitudinal Neuroimaging in Sturge-Weber Syndrome
A NA study of Sturge-Weber Syndrome, sponsored by Wayne State University.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT04517565: Recruiting NA study of Sturge-Weber Syndrome, sponsored by Wayne State University.
NCT04517565 is a NA study of Sturge-Weber Syndrome that is actively recruiting participants, run by Wayne State University. The registered enrollment target is 80 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04517565, a NA study of Sturge-Weber Syndrome, is actively recruiting participants, sponsored by Wayne State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
In this project the accuracy of a novel, rapid magnetic resonance imaging (MRI) approach to detect brain abnormalities in patients with Sturge-Weber syndrome (SWS) will be tested; this new imaging approach, that can create multiple types of MR images in about 5 minutes, without contrast administration (and sedation even in young children), can be also readily applied in other pediatric brain disorders in the future. The investigators will also study how advanced MRI, including susceptibility-weighted and diffusion tensor imaging can detect detailed signs of brain vascular and neuronal reorganization that helps improve neurological and cognitive outcome of children and young adults with SWS, who could benefit from targeted interventions in the future to minimize neurocognitive deficits in affected patients. All enrolled subjects will undergo advanced brain MRI and neurocognitive evaluation to achieve these goals.
Primary Outcome
Presence (score 1) vs. absence (score 0) of SWS brain abnormalities in each of 8 cerebral lobes using fast MRI compared with the same scores obtained from standard MRI, obtained in the same imaging session, as the ground truth.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Brain magnetic resonance imaging
- BEHAVIORAL Neuro-psychology testing
Study Locations (1)
Michigan
- Wayne State University / Children's Hospital of Michigan - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2020-03-01 |
| Est. Completion | 2026-02-28 |
| Phase | NA |
What NCT04517565 shows while recruiting
NCT04517565 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Sturge-Weber Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Brain magnetic resonance imaging is the first listed.
NCT04517565 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT04517565 about?
NCT04517565 is a clinical study titled "Longitudinal Neuroimaging in Sturge-Weber Syndrome". In this project the accuracy of a novel, rapid magnetic resonance imaging (MRI) approach to detect brain abnormalities in patients with Sturge-Weber syndrome (SWS) will be tested; this new imaging approach, that can create multiple types of MR images in about 5 minutes, without contrast administrati...
What is the current status of trial NCT04517565?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2020-03-01. Estimated completion is 2026-02-28.
What conditions does trial NCT04517565 study?
This clinical trial studies the following conditions: Sturge-Weber Syndrome.
What interventions are being tested in trial NCT04517565?
The interventions under investigation include: Brain magnetic resonance imaging (DIAGNOSTIC_TEST), Neuro-psychology testing (BEHAVIORAL).
Who is sponsoring clinical trial NCT04517565?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04517565 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sturge-Weber Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04517565's enrollment target sits among peer trials
80 994th of 2000 higher than 941 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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