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NCT04516148 · ClinicalTrials.gov registry record · Phase 4
A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting
A Phase 4 study of Surgery and Burn, sponsored by Medstar Health Research Institute.
- Completed
- Registry status
- Phase 4
- Development phase
- 32
- Enrollment target
- 1
- Study location
NCT04516148: Completed Phase 4 study of Surgery and Burn, sponsored by Medstar Health Research Institute.
NCT04516148 is a Phase 4 study of Surgery and Burn that has completed, run by Medstar Health Research Institute. The registered enrollment target is 32 participants, below the 52,851-participant average among 120 other Surgery trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04516148, a Phase 4 study of Surgery and Burn, has completed, sponsored by Medstar Health Research Institute.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 32 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study if to evaluate the effectiveness of prophylactic antibiotics given during surgery in reducing the concentration of bacteria in a burn wound after surgery.
Primary Outcome
The primary effectiveness endpoint is a statistically significant reduction in the burn wound bacterial concentration in wounds where patients received antibiotics. Samples (tissue swabs and punch biopsies) obtained intraoperatively following wound bed preparation will be compared to samples (tissue swabs and punch biopsies) obtained from the wound within six hours of initial postoperative dressing take-down.
Conditions Studied
Interventions
- DRUG Cefazolin
- DRUG Clindamycin
Study Locations (1)
District of Columbia
- MedStar Washington Hospital Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2018-05-29 |
| Est. Completion | 2020-10-30 |
| Phase | Phase 4 |
What the finished NCT04516148 record still lists
NCT04516148 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 52,851-participant average among 120 other Surgery trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Surgery appearing as the primary indexed condition, and to 2 interventions - of which Cefazolin is the first listed.
NCT04516148 reports a single indexed study location in District of Columbia.
Frequently Asked Questions
What is clinical trial NCT04516148 about?
NCT04516148 is a clinical study titled "A Randomized, Controlled Trial of the Effectiveness of Perioperative Antibiotics for Reduction of Burn Wound Bacterial Concentration Following Grafting". The purpose of this study if to evaluate the effectiveness of prophylactic antibiotics given during surgery in reducing the concentration of bacteria in a burn wound after surgery.
What is the current status of trial NCT04516148?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 32 participants. The study started on 2018-05-29. Estimated completion is 2020-10-30.
What conditions does trial NCT04516148 study?
This clinical trial studies the following conditions: Surgery, Burn, Infection Wound.
What interventions are being tested in trial NCT04516148?
The interventions under investigation include: Cefazolin (DRUG), Clindamycin (DRUG).
Who is sponsoring clinical trial NCT04516148?
This trial is sponsored by Medstar Health Research Institute, which has 115 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04516148 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Surgery
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04516148's enrollment target sits among peer trials
32 103rd of 120 higher than 15 of 120 other Surgery trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Surgery trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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