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NCT04502225 · ClinicalTrials.gov registry record · NA
Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure
A NA study of Autonomic Failure and Supine Hypertension, sponsored by Vanderbilt University Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 44
- Enrollment target
- 1
- Study location
NCT04502225: Recruiting NA study of Autonomic Failure and Supine Hypertension, sponsored by Vanderbilt University Medical Center.
NCT04502225 is a NA study of Autonomic Failure and Supine Hypertension that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 44 participants, above the 35-participant average among 11 other Autonomic Failure trials with a reported enrollment target (26% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04502225, a NA study of Autonomic Failure and Supine Hypertension, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 44 participants
- Enrollment target
- 1
- Study location
Study Summary
Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective at lowering supine blood pressure, these approaches may be utilized to treat supine hypertension non-pharmacologically. Raising the head of the bed decreases the amount of blood returning to the heart due to the effects of gravity. In this case, the decreased blood return to the heart may decrease blood pressure.
Primary Outcome
Maximal change from baseline in systolic blood pressure during the night
Conditions Studied
Interventions
- OTHER Tilt
- OTHER Elevated trunk
- OTHER Tilt - In home
- OTHER Elevated Trunk - In home
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2020-08-21 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT04502225 shows while recruiting
NCT04502225 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, above the 35-participant average among 11 other Autonomic Failure trials with a reported enrollment target (26% higher).
The record links to 2 conditions, with Autonomic Failure appearing as the primary indexed condition, and to 4 interventions - of which Tilt is the first listed.
NCT04502225 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT04502225 about?
NCT04502225 is a clinical study titled "Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure". Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is e...
What is the current status of trial NCT04502225?
This trial is currently recruiting. It is a NA study. The enrollment target is 44 participants. The study started on 2020-08-21. Estimated completion is 2026-12-31.
What conditions does trial NCT04502225 study?
This clinical trial studies the following conditions: Autonomic Failure, Supine Hypertension.
What interventions are being tested in trial NCT04502225?
The interventions under investigation include: Tilt (OTHER), Elevated trunk (OTHER), Tilt - In home (OTHER), Elevated Trunk - In home (OTHER).
Who is sponsoring clinical trial NCT04502225?
This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04502225 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Autonomic Failure
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04502225's enrollment target sits among peer trials
44 3rd of 11 higher than 9 of 11 other Autonomic Failure trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Autonomic Failure trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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