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NCT04502225 · ClinicalTrials.gov registry record · NA

Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure

A NA study of Autonomic Failure and Supine Hypertension, sponsored by Vanderbilt University Medical Center.

Recruiting
Registry status
NA
Development phase
44
Enrollment target
1
Study location

NCT04502225 is a NA study of Autonomic Failure and Supine Hypertension that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 44 participants, above the 35-participant average among 11 other Autonomic Failure trials with a reported enrollment target (26% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT04502225, a NA study of Autonomic Failure and Supine Hypertension, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.

RECRUITING
Registry status
NA
Development phase
44 participants
Enrollment target
1
Study location

Study Summary

Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is effective at lowering supine blood pressure, these approaches may be utilized to treat supine hypertension non-pharmacologically. Raising the head of the bed decreases the amount of blood returning to the heart due to the effects of gravity. In this case, the decreased blood return to the heart may decrease blood pressure.

Interventions

  • OTHER Tilt
  • OTHER Elevated trunk
  • OTHER Tilt - In home
  • OTHER Elevated Trunk - In home

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2020-08-21
Est. Completion 2026-12-31
Phase NA

What the Registry Record Tells You About NCT04502225

The ClinicalTrials.gov registry entry for NCT04502225 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 35-participant average among 11 other Autonomic Failure trials with a reported enrollment target (26% higher). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Autonomic Failure appearing as the primary indexed condition, and to 4 interventions - of which Tilt is the first listed.

NCT04502225 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT04502225 about?

NCT04502225 is a clinical study titled "Effect of Raised Head of the Bed on Lying Blood Pressure in Autonomic Failure". Many persons with autonomic failure often have high blood pressure when lying down (supine hypertension). This study is exploring the impact of decreased venous return to the heart (achieved by raising the head of the bed) to lessen supine blood pressure. If decreased venous return to the heart is e...

What is the current status of trial NCT04502225?

This trial is currently recruiting. It is a NA study. The enrollment target is 44 participants. The study started on 2020-08-21. Estimated completion is 2026-12-31.

What conditions does trial NCT04502225 study?

This clinical trial studies the following conditions: Autonomic Failure, Supine Hypertension.

What interventions are being tested in trial NCT04502225?

The interventions under investigation include: Tilt (OTHER), Elevated trunk (OTHER), Tilt - In home (OTHER), Elevated Trunk - In home (OTHER).

Who is sponsoring clinical trial NCT04502225?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04502225 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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