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RECRUITING NA

Sensory-specific Peripheral Stimulation for Tremor Management

NCT04501133 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to understand the neurophysiological mechanisms of peripheral electrical stimulation (PES) in modulating supraspinal tremorogenic input to motoneurons. For this purpose, the investigators will use transcutaneous PES, high-density electromyography (HD-EMG), transcranial magnetic stimulation (TMS), electroencephalography (EEG), magnetic resonance imaging (MRI), and neuromusculoskeletal modelling. This study will be carried out in both healthy participants and patients with essential tremor (ET) and Parkinson's disease (PD).

Interventions

  • DEVICE Peripheral electrical stimulation
  • DEVICE Single pulse TMS

Study Locations (1)

Illinois

  • Shirley Ryan AbilityLab — Chicago

Trial Details

FieldValue
Enrollment Target 180 participants
Start Date 2020-09-01
Est. Completion 2025-12
Phase NA

Sponsor

Shirley Ryan AbilityLab

274 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04501133

The ClinicalTrials.gov registry entry for NCT04501133 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 180 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Shirley Ryan AbilityLab, which has 274 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Parkinson's Disease appearing as the primary indexed condition, and to 2 interventions — of which Peripheral electrical stimulation is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04501133 reports 1 study location spanning 1 distinct geographic area — top geographies include Illinois. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04501133 about?

NCT04501133 is a clinical study titled "Sensory-specific Peripheral Stimulation for Tremor Management". The purpose of this study is to understand the neurophysiological mechanisms of peripheral electrical stimulation (PES) in modulating supraspinal tremorogenic input to motoneurons. For this purpose, the investigators will use transcutaneous PES, high-density electromyography (HD-EMG), transcranial m...

What is the current status of trial NCT04501133?

This trial is currently recruiting. It is a NA study. The enrollment target is 180 participants. The study started on 2020-09-01. Estimated completion is 2025-12.

What conditions does trial NCT04501133 study?

This clinical trial studies the following conditions: Parkinson's Disease, Essential Tremor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04501133?

The interventions under investigation include: Peripheral electrical stimulation (DEVICE), Single pulse TMS (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04501133?

This trial is sponsored by Shirley Ryan AbilityLab, which has 274 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04501133 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial