Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04472702 · ClinicalTrials.gov registry record · NA
Fluoroscopic Versus Ultrasound Guidance for Cooled Radiofrequency Ablation of Geniculate Nerves in Knee Osteoarthritis: A Randomized Control Trial
A NA study of Knee Osteoarthritis, sponsored by University of California, Davis.
- Recruiting
- Registry status
- NA
- Development phase
- 90
- Enrollment target
- 2
- Study locations
NCT04472702: Recruiting NA study of Knee Osteoarthritis, sponsored by University of California, Davis.
NCT04472702 is a NA study of Knee Osteoarthritis that is actively recruiting participants, run by University of California, Davis. The registered enrollment target is 90 participants, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (70% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04472702, a NA study of Knee Osteoarthritis, is actively recruiting participants, sponsored by University of California, Davis.
- RECRUITING
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
- 2
- Study locations
Study Summary
Cooled radiofrequency ablation (cRFA) of the knee geniculate nerves is a promising treatment option for knee osteoarthritis, but has variable efficacy. Fluoroscopy is the typical guidance of choice, but uses bony landmarks to target these nerves which have variable positions around the knee. Alternatively, ultrasound allows for targeting based on visualization of bony landmarks, the nerves, and their accompanying vascular structures, and thus may offer greater accuracy. However, there are few studies which directly compare the clinical efficacy of these two guidance options. This study will compare these two options.
Primary Outcome
The objective is to rate patient's reported pain. The NPRS asks for a number between zero and ten that fits best to the subject's pain intensity, with zero as "no pain at all" and ten representing "the worst pain ever possible". It has a similar minimal clinically significant difference (20%) as the visual analog scale and can be administered via a phone interview.
Conditions Studied
Interventions
- PROCEDURE cRFA
Study Locations (2)
California
- UC Davis Health - Sacramento
New York
- University of Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2022-02-02 |
| Est. Completion | 2026-05-01 |
| Phase | NA |
What NCT04472702 shows while recruiting
NCT04472702 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 304-participant average among 101 other Knee Osteoarthritis trials with a reported enrollment target (70% lower).
The record links to 1 condition, with Knee Osteoarthritis appearing as the primary indexed condition, and to 1 intervention - of which cRFA is the first listed.
NCT04472702 reports a single indexed study location in California, New York.
Frequently Asked Questions
What is clinical trial NCT04472702 about?
NCT04472702 is a clinical study titled "Fluoroscopic Versus Ultrasound Guidance for Cooled Radiofrequency Ablation of Geniculate Nerves in Knee Osteoarthritis: A Randomized Control Trial". Cooled radiofrequency ablation (cRFA) of the knee geniculate nerves is a promising treatment option for knee osteoarthritis, but has variable efficacy. Fluoroscopy is the typical guidance of choice, but uses bony landmarks to target these nerves which have variable positions around the knee. Alterna...
What is the current status of trial NCT04472702?
This trial is currently recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2022-02-02. Estimated completion is 2026-05-01.
What conditions does trial NCT04472702 study?
This clinical trial studies the following conditions: Knee Osteoarthritis.
What interventions are being tested in trial NCT04472702?
The interventions under investigation include: cRFA (PROCEDURE).
Who is sponsoring clinical trial NCT04472702?
This trial is sponsored by University of California, Davis, which has 657 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04472702 being conducted?
This trial has 2 study locations across California, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Knee Osteoarthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04472702's enrollment target sits among peer trials
90 49th of 101 higher than 52 of 101 other Knee Osteoarthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Knee Osteoarthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis
RECRUITING · NA
-
Focused Extracorporeal Shockwave Therapy for Knee Arthritis
RECRUITING · NA
-
Mechanical Alignment Vs Kalipered Kinematic Alignment Total Knee Arthroplasty
RECRUITING · NA
-
Investigating Patient Satisfaction With Smart Knee Implants
RECRUITING · NA
-
Gait Rehabilitation to Treat FastOA
RECRUITING · NA
-
Knee Biofeedback Rehabilitation Through Game Therapy
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02521311 · 90 participants · Phase 2
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)
- NCT02939573 · 90 participants · Phase 2
A Randomized Multicenter Study for Isolated Skin Vasculitis
- NCT03128879 · 90 participants · Phase 2
Venetoclax With Ibrutinib or Acalabrutinib in Pts. With High-risk CLL
- NCT03184038 · 90 participants · NA
Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI