Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04449445 · ClinicalTrials.gov registry record · NA
Perioperative Nutritional Optimization in Head and Neck Cancer Patients
A NA study of Head and Neck Cancer, sponsored by University of Illinois at Chicago.
- Recruiting
- Registry status
- NA
- Development phase
- 300
- Enrollment target
- 1
- Study location
NCT04449445: Recruiting NA study of Head and Neck Cancer, sponsored by University of Illinois at Chicago.
NCT04449445 is a NA study of Head and Neck Cancer that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 300 participants, above the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (15% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04449445, a NA study of Head and Neck Cancer, is actively recruiting participants, sponsored by University of Illinois at Chicago.
- RECRUITING
- Registry status
- NA
- Development phase
- 300 participants
- Enrollment target
- 1
- Study location
Study Summary
To determine whether nutritional optimization in head and neck cancer patients undergoing major surgery will decrease post-operative wound complications. The Investigators hypothesize that nutritional supplementation with Nestle Impact Advanced Recovery (AR) will decrease the rate of wound complications after surgery
Primary Outcome
Assess the rate of post-operative wound infection
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Isocaloric and iso-nitrogenous standard enteral tube feeds
- DIETARY_SUPPLEMENT Nestle IMPACT AR
Study Locations (1)
Illinois
- University of Illinois at Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2022-05-10 |
| Est. Completion | 2026-11 |
| Phase | NA |
What NCT04449445 shows while recruiting
NCT04449445 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, above the 260-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (15% higher).
The record links to 1 condition, with Head and Neck Cancer appearing as the primary indexed condition, and to 2 interventions - of which Isocaloric and iso-nitrogenous standard enteral tube feeds is the first listed.
NCT04449445 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04449445 about?
NCT04449445 is a clinical study titled "Perioperative Nutritional Optimization in Head and Neck Cancer Patients". To determine whether nutritional optimization in head and neck cancer patients undergoing major surgery will decrease post-operative wound complications. The Investigators hypothesize that nutritional supplementation with Nestle Impact Advanced Recovery (AR) will decrease the rate of wound complicat...
What is the current status of trial NCT04449445?
This trial is currently recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2022-05-10. Estimated completion is 2026-11.
What conditions does trial NCT04449445 study?
This clinical trial studies the following conditions: Head and Neck Cancer.
What interventions are being tested in trial NCT04449445?
The interventions under investigation include: Isocaloric and iso-nitrogenous standard enteral tube feeds (DIETARY_SUPPLEMENT), Nestle IMPACT AR (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT04449445?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04449445 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Head and Neck Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04449445's enrollment target sits among peer trials
300 35th of 250 higher than 214 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Prospective Evaluation of Pencil Beam Scanning Proton Therapy for Previously Irradiated Tumors
RECRUITING · NA
-
Improving Care for Rural Patients With Solid Tumors
RECRUITING · NA
-
Study of Non-invasive Acupuncture-like Transcutaneous Electrical Nerve Stimulation (Altens) to Help Alleviate Xerostomia After Radiation Therapy for Cancers of the Head and Neck
RECRUITING · NA
-
A Study Evaluating the Integrative Medicine at Home (IM@HOME) Program in People With Cancer
RECRUITING · NA
-
Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients
RECRUITING · NA
-
Axoguard HA Plus Nerve Protector to Reduce Post-operative Neck and Shoulder Dysfunction in Patients Undergoing Neck Dissection
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00353483 · 300 participants
Effect of Neoadjuvant or Adjuvant Systemic Therapy on Breast Cancers, Bone Marrow Cancer Cells, and Circulating Cancer Cells
- NCT00588185 · 300 participants · NA
[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer
- NCT00682032 · 300 participants · NA
The Effect of Beta-glucan in Non-Small Cell Lung Cancer
- NCT00870064 · 300 participants · NA
The Treatment of Type I Open Fractures in Pediatrics
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI