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NCT04424576 · ClinicalTrials.gov registry record
Ovarian Morphology in Girls
A clinical trial of Puberty and Amenorrhea, sponsored by Cornell University.
- Recruiting
- Registry status
- 60
- Enrollment target
- 3
- Study locations
NCT04424576: Recruiting study of Puberty and Amenorrhea, sponsored by Cornell University.
NCT04424576 is a study of Puberty and Amenorrhea that is actively recruiting participants, run by Cornell University. The registered enrollment target is 60 participants, below the 90-participant average among 8 other Puberty trials with a reported enrollment target (33% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04424576, a study of Puberty and Amenorrhea, is actively recruiting participants, sponsored by Cornell University.
- RECRUITING
- Registry status
- 60 participants
- Enrollment target
- 3
- Study locations
Study Summary
Establishment of regular menstrual cycles is a key component of reproductive maturation and a recognized vital sign for health and well-being. Irregular menstrual cycles are especially common for the first 2-3 years after an adolescent's first menstrual period (i.e., menarche), which delays the identification and diagnosis of early reproductive disturbances such as polycystic ovary syndrome (PCOS). The purpose of this research study is to determine whether the ovary can serve as a reliable predictor of normal or abnormal development by following the trajectory of ovarian morphology in conjunction with menstrual cyclicity using 3D transabdominal ultrasound imaging in a prospective cohort study of adolescents. A secondary objective is to identify potential environmental factors such as diet and the gut microbiome which influence the trajectory towards normal or abnormal reproductive development.
Conditions Studied
Study Locations (3)
New York
- Cornell University - Human Metabolic Research Unit - Ithaca
- University of Rochester, Strong Fertility Center - Rochester
Missouri
- Children's Mercy Hospital - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2020-01-31 |
| Est. Completion | 2025-03-31 |
What NCT04424576 shows while recruiting
NCT04424576 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 90-participant average among 8 other Puberty trials with a reported enrollment target (33% lower).
The record links to 3 conditions, with Puberty appearing as the primary indexed condition, and to 0 interventions.
NCT04424576 reports a single indexed study location in New York, Missouri.
Frequently Asked Questions
What is clinical trial NCT04424576 about?
NCT04424576 is a clinical study titled "Ovarian Morphology in Girls". Establishment of regular menstrual cycles is a key component of reproductive maturation and a recognized vital sign for health and well-being. Irregular menstrual cycles are especially common for the first 2-3 years after an adolescent's first menstrual period (i.e., menarche), which delays the iden...
What is the current status of trial NCT04424576?
This trial is currently recruiting. The enrollment target is 60 participants. The study started on 2020-01-31. Estimated completion is 2025-03-31.
What conditions does trial NCT04424576 study?
This clinical trial studies the following conditions: Puberty, Amenorrhea, Oligomenorrhea.
Who is sponsoring clinical trial NCT04424576?
This trial is sponsored by Cornell University, which has 66 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04424576 being conducted?
This trial has 3 study locations across Missouri, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Puberty
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04424576's enrollment target sits among peer trials
60 5th of 8 higher than 4 of 8 other Puberty trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Puberty trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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