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NCT04418427 · ClinicalTrials.gov registry record · Phase 2

ADVM-022 Intravitreal Gene Therapy for DME

A Phase 2 study, sponsored by Adverum Biotechnologies.

Completed
Registry status
Phase 2
Development phase
36
Enrollment target

NCT04418427 is a Phase 2 study that has completed, run by Adverum Biotechnologies. The registered enrollment target is 36 participants.

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The verdict

NCT04418427, a Phase 2 study, has completed, sponsored by Adverum Biotechnologies.

COMPLETED
Registry status
Phase 2
Development phase
36 participants
Enrollment target

Study Summary

A Phase 2, Multi-Center, Randomized, Double-Masked\*, Active Controlled Study of ADVM-022 (AAV.7m8-aflibercept) in Subjects with Diabetic Macular Edema \[INFINITY\]

Interventions

  • BIOLOGICAL Aflibercept
  • BIOLOGICAL 6E11 vg/eye of ADVM-022
  • BIOLOGICAL 2E11 vg/eye of ADVM-022

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2020-05-28
Est. Completion 2023-06-14
Phase Phase 2

Sponsor

Adverum Biotechnologies

10 total trials

What the Registry Record Tells You About NCT04418427

The ClinicalTrials.gov registry entry for NCT04418427 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Adverum Biotechnologies, which has 10 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Aflibercept is the first listed.

NCT04418427 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04418427 about?

NCT04418427 is a clinical study titled "ADVM-022 Intravitreal Gene Therapy for DME". A Phase 2, Multi-Center, Randomized, Double-Masked\*, Active Controlled Study of ADVM-022 (AAV.7m8-aflibercept) in Subjects with Diabetic Macular Edema \[INFINITY\]

What is the current status of trial NCT04418427?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2020-05-28. Estimated completion is 2023-06-14.

What interventions are being tested in trial NCT04418427?

The interventions under investigation include: Aflibercept (BIOLOGICAL), 6E11 vg/eye of ADVM-022 (BIOLOGICAL), 2E11 vg/eye of ADVM-022 (BIOLOGICAL).

Who is sponsoring clinical trial NCT04418427?

This trial is sponsored by Adverum Biotechnologies, which has 10 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.