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ACTIVE NOT RECRUITING Phase 2

Olaparib With Ceralasertib in Recurrent Osteosarcoma

NCT04417062 · View on ClinicalTrials.gov ↗

Study Summary

This study is being done in order to evaluate the effectiveness of using two drugs (olaparib and ceralasertib) to treat patients with osteosarcoma that has not responded to treatment or has come back after treatment The names of the study drugs involved in this study are: * Olaparib * Ceralasertib

Interventions

  • DRUG Olaparib
  • DRUG Ceralasertib

Study Locations (4)

California

  • UCSF Benioff Children's Hospital; UCSF Pediatrics Hematology Oncology — San Francisco

Massachusetts

  • Dana Farber Cancer Institite — Boston

New York

  • Memorial Sloan Kettering — New York

Texas

  • MD Anderson — Houston

Trial Details

FieldValue
Enrollment Target 63 participants
Start Date 2020-11-24
Est. Completion 2026-06-01
Phase Phase 2

Sponsor

Dana-Farber Cancer Institute

819 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04417062

The ClinicalTrials.gov registry entry for NCT04417062 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 63 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Dana-Farber Cancer Institute, which has 819 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Osteosarcoma appearing as the primary indexed condition, and to 2 interventions — of which Olaparib is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT04417062 reports 4 study locations spanning 4 distinct geographic areas — top geographies include California, Massachusetts, New York. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT04417062 about?

NCT04417062 is a clinical study titled "Olaparib With Ceralasertib in Recurrent Osteosarcoma". This study is being done in order to evaluate the effectiveness of using two drugs (olaparib and ceralasertib) to treat patients with osteosarcoma that has not responded to treatment or has come back after treatment The names of the study drugs involved in this study are: * Olaparib * Ceralasertib

What is the current status of trial NCT04417062?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 63 participants. The study started on 2020-11-24. Estimated completion is 2026-06-01.

What conditions does trial NCT04417062 study?

This clinical trial studies the following conditions: Osteosarcoma, Osteosarcoma Recurrent. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT04417062?

The interventions under investigation include: Olaparib (DRUG), Ceralasertib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT04417062?

This trial is sponsored by Dana-Farber Cancer Institute, which has 819 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT04417062 being conducted?

This trial has 4 study locations across California, Massachusetts, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial