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NCT04408313 · ClinicalTrials.gov registry record · Phase 2

Extended Release Naltrexone Versus Extended Release Buprenorphine With Individuals Leaving Jail

A Phase 2 study of Opioid Use Disorder, sponsored by Friends Research Institute.

Active
Registry status
Phase 2
Development phase
240
Enrollment target
1
Study location

NCT04408313 is a Phase 2 study of Opioid Use Disorder that is active but no longer recruiting, run by Friends Research Institute. The registered enrollment target is 240 participants, below the 4,655-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04408313, a Phase 2 study of Opioid Use Disorder, is active but no longer recruiting, sponsored by Friends Research Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
240 participants
Enrollment target
1
Study location

Study Summary

The proposed study is a Type 1 hybrid effectiveness-implementation trial. Individuals with opioid use disorder in county jails throughout the state of Maryland will be randomly assigned within gender within jail to one of two groups: Arm 1. XR-B (n=120). XR-B in jail followed by 6 monthly injections post-release at a community treatment program. Arm 2. XR-NTX (n=120). One injection of XR-NTX in jail, followed by 6 monthly injections post-release at a community treatment program.

Conditions Studied

Opioid Use Disorder

Interventions

  • DRUG XR-B
  • DRUG XR-NTX

Study Locations (1)

Maryland

  • Friends Research Institute - Baltimore

Trial Details

FieldValue
Enrollment Target 240 participants
Start Date 2020-10-28
Est. Completion 2026-05-31
Phase Phase 2

Sponsor

Friends Research Institute

41 total trials

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What the Registry Record Tells You About NCT04408313

The ClinicalTrials.gov registry entry for NCT04408313 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 240 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,655-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (95% lower). The listed sponsor is Friends Research Institute, which has 41 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Opioid Use Disorder appearing as the primary indexed condition, and to 2 interventions - of which XR-B is the first listed.

NCT04408313 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT04408313 about?

NCT04408313 is a clinical study titled "Extended Release Naltrexone Versus Extended Release Buprenorphine With Individuals Leaving Jail". The proposed study is a Type 1 hybrid effectiveness-implementation trial. Individuals with opioid use disorder in county jails throughout the state of Maryland will be randomly assigned within gender within jail to one of two groups: Arm 1. XR-B (n=120). XR-B in jail followed by 6 monthly injections...

What is the current status of trial NCT04408313?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 240 participants. The study started on 2020-10-28. Estimated completion is 2026-05-31.

What conditions does trial NCT04408313 study?

This clinical trial studies the following conditions: Opioid Use Disorder.

What interventions are being tested in trial NCT04408313?

The interventions under investigation include: XR-B (DRUG), XR-NTX (DRUG).

Who is sponsoring clinical trial NCT04408313?

This trial is sponsored by Friends Research Institute, which has 41 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04408313 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.