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NCT04354077 · ClinicalTrials.gov registry record · NA

Deep Brain Stimulation Effects In Patients With Opioid Use Disorder

A NA study of Opioid Use Disorder, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).

Recruiting
Registry status
NA
Development phase
3
Enrollment target
1
Study location

NCT04354077: Recruiting NA study of Opioid Use Disorder, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).

NCT04354077 is a NA study of Opioid Use Disorder that is actively recruiting participants, run by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute). The registered enrollment target is 3 participants, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04354077, a NA study of Opioid Use Disorder, is actively recruiting participants, sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute).

RECRUITING
Registry status
NA
Development phase
3 participants
Enrollment target
1
Study location

Study Summary

This is a pilot study to evaluate the safety and efficacy of deep brain stimulation (DBS) of the nucleus accumbens (NAc) as adjunctive treatment for treatment-refractory opioid use disorder. This study will include 3 individuals with opioid use disorder and relapsing opioid use despite active participation in a drug addiction treatment program.

Primary Outcome

Percentage of subjects achieving opioid abstinence

Conditions Studied

Opioid Use Disorder

Interventions

  • DEVICE DBS of the NAc

Study Locations (1)

Pennsylvania

  • AHN Allegheny General Hospital - Pittsburgh

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2022-02-07
Est. Completion 2030-01
Phase NA
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)

34 total trials

What NCT04354077 shows while recruiting

NCT04354077 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (100% lower).

The record links to 1 condition, with Opioid Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which DBS of the NAc is the first listed.

NCT04354077 reports a single indexed study location in Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT04354077 about?

NCT04354077 is a clinical study titled "Deep Brain Stimulation Effects In Patients With Opioid Use Disorder". This is a pilot study to evaluate the safety and efficacy of deep brain stimulation (DBS) of the nucleus accumbens (NAc) as adjunctive treatment for treatment-refractory opioid use disorder. This study will include 3 individuals with opioid use disorder and relapsing opioid use despite active partic...

What is the current status of trial NCT04354077?

This trial is currently recruiting. It is a NA study. The enrollment target is 3 participants. The study started on 2022-02-07. Estimated completion is 2030-01.

What conditions does trial NCT04354077 study?

This clinical trial studies the following conditions: Opioid Use Disorder.

What interventions are being tested in trial NCT04354077?

The interventions under investigation include: DBS of the NAc (DEVICE).

Who is sponsoring clinical trial NCT04354077?

This trial is sponsored by Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute), which has 34 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04354077 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Opioid Use Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04354077's enrollment target sits among peer trials

3 258th of 257 the lowest of 257 other Opioid Use Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Opioid Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT04354077

Source: ClinicalTrials.gov NCT04354077, the US trial registry maintained by the National Library of Medicine. NCT04354077 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.