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NCT04322357 · ClinicalTrials.gov registry record · Phase 2
Twice Weekly Steroids and Exercise as Therapy for DMD
A Phase 2 study, sponsored by University of Florida.
- Completed
- Registry status
- Phase 2
- Development phase
- 21
- Enrollment target
NCT04322357 is a Phase 2 study that has completed, run by University of Florida. The registered enrollment target is 21 participants.
The verdict
NCT04322357, a Phase 2 study, has completed, sponsored by University of Florida.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 21 participants
- Enrollment target
Study Summary
The study team will determine the potential of low dose twice weekly prednisone and whether exercise training can synergize to delay disease progression and improve muscle strength/physical function in boys with Duchenne muscular dystrophy (DMD). Current standard of care (daily prednisone) is associated with adverse side effects. Evidence from DMD mouse models suggest that weekly dosing provides same efficacy without side effects. Appropriate exercise may also benefit but this area has not been adequately explored.
Interventions
- DRUG Prednisone
- BEHAVIORAL Exercise Training on standard steroid regimen
- DRUG Exercise training on twice-weekly steroids
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2020-07-30 |
| Est. Completion | 2025-09-04 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04322357
The ClinicalTrials.gov registry entry for NCT04322357 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Prednisone is the first listed.
NCT04322357 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT04322357 about?
NCT04322357 is a clinical study titled "Twice Weekly Steroids and Exercise as Therapy for DMD". The study team will determine the potential of low dose twice weekly prednisone and whether exercise training can synergize to delay disease progression and improve muscle strength/physical function in boys with Duchenne muscular dystrophy (DMD). Current standard of care (daily prednisone) is associ...
What is the current status of trial NCT04322357?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 21 participants. The study started on 2020-07-30. Estimated completion is 2025-09-04.
What interventions are being tested in trial NCT04322357?
The interventions under investigation include: Prednisone (DRUG), Exercise Training on standard steroid regimen (BEHAVIORAL), Exercise training on twice-weekly steroids (DRUG).
Who is sponsoring clinical trial NCT04322357?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
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