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NCT04294966 · ClinicalTrials.gov registry record · Early Phase 1
Age-Related Effects of THC
A Early Phase 1 study of Adolescent Behavior and THC, sponsored by University of Chicago.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 24
- Enrollment target
- 2
- Study locations
NCT04294966: Completed Early Phase 1 study of Adolescent Behavior and THC, sponsored by University of Chicago.
NCT04294966 is a Early Phase 1 study of Adolescent Behavior and THC that has completed, run by University of Chicago. The registered enrollment target is 24 participants, below the 329-participant average among 46 other Adolescent Behavior trials with a reported enrollment target (93% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04294966, a Early Phase 1 study of Adolescent Behavior and THC, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 24 participants
- Enrollment target
- 2
- Study locations
Study Summary
Increased accessibility to cannabis and its primary psychoactive constituent THC has raised public health concerns. One major concern surrounds the potential risks associated with acute THC intoxication and who might be most at risk. A second major concern is the need to develop sensitive measures that can detect THC intoxication after recent use and enable robust comparisons of intoxication to determine sources of risk. One potential source of risk is age, specifically during the period of adolescence.
Primary Outcome
The POMS measures individuals' mood states. This is a validated scale to measure positive and negative mood states. The POMS consists of 72 mood adjectives rated on a Likert scale from 0 (not at all) to 4 (extremely), divided into 8 subscales: Friendliness, Anxiety, Elation, Anger, Fatigue, Depression, Confusion and Vigor, and two composite scales: Positive Mood (Elation minus Depression) and Arousal (Vigor plus Anxiety minus Confusion plus Fatigue). Scoring of this instrument provides a global
Conditions Studied
Interventions
- DRUG Dronabinol
- DRUG Dextrose
Study Locations (2)
Illinois
- University of Chicago Hospital - Chicago
- University of Chicago - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2020-03-10 |
| Est. Completion | 2021-05-01 |
| Phase | Early Phase 1 |
What the finished NCT04294966 record still lists
NCT04294966 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 329-participant average among 46 other Adolescent Behavior trials with a reported enrollment target (93% lower).
The record links to 3 conditions, with Adolescent Behavior appearing as the primary indexed condition, and to 2 interventions - of which Dronabinol is the first listed.
NCT04294966 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04294966 about?
NCT04294966 is a clinical study titled "Age-Related Effects of THC". Increased accessibility to cannabis and its primary psychoactive constituent THC has raised public health concerns. One major concern surrounds the potential risks associated with acute THC intoxication and who might be most at risk. A second major concern is the need to develop sensitive measures t...
What is the current status of trial NCT04294966?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 24 participants. The study started on 2020-03-10. Estimated completion is 2021-05-01.
What conditions does trial NCT04294966 study?
This clinical trial studies the following conditions: Adolescent Behavior, THC, Tolerance.
What interventions are being tested in trial NCT04294966?
The interventions under investigation include: Dronabinol (DRUG), Dextrose (DRUG).
Who is sponsoring clinical trial NCT04294966?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04294966 being conducted?
This trial has 2 study locations across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04294966's enrollment target sits among peer trials
24 47th of 46 the lowest of 46 other Adolescent Behavior trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Adolescent Behavior trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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