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NCT04290754 · ClinicalTrials.gov registry record · NA
PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents
A NA study of Depression, sponsored by University of Illinois at Chicago.
- Active
- Registry status
- NA
- Development phase
- 636
- Enrollment target
- 1
- Study location
NCT04290754: Active NA study of Depression, sponsored by University of Illinois at Chicago.
NCT04290754 is a NA study of Depression that is active but no longer recruiting, run by University of Illinois at Chicago. The registered enrollment target is 636 participants, below the 785-participant average among 679 other Depression trials with a reported enrollment target (19% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04290754, a NA study of Depression, is active but no longer recruiting, sponsored by University of Illinois at Chicago.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 636 participants
- Enrollment target
- 1
- Study location
Study Summary
PATH (Promoting AdolescenT Health) 2 Purpose is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral \& Interpersonal Training (CATCH-IT) and Teens Achieving Mastery over Stress (TEAMS), to intervene early to prevent depressive illness and potentially other common mental health disorders. Using cluster randomization, 564 participants eligible for the study will be offered one of two different depression prevention programs in multiple sites in Chicagoland, Rockford, Illinois; Dixon, Illinois; and Louisville, Kentucky. In response to the Coronavirus Disease 2019 (COVID-19) pandemic, we will employ a public health media campaign to recruit a second cohort of 100 adolescents state-wide in Illinois, Kentucky, and Massachusetts individually randomized to either intervention. The study will also assess teens', parents' and providers' experiences with each intervention approach. Finally, we will examine the impact of the COVID-19 pandemic on adolescents at-risk for depression who are enrolled in our study.
Primary Outcome
Time will be measured to nearest minute for all intervention related activities including initial screening, engagement phone calls, use of CATCH-IT, TEAMS group activities, including travel time to and from TEAMS groups. Time will be measured from adolescent, family, practice, community center, healthcare organization, health system perspective. For time that cannot be directly measured by study staff, the investigators will sample direct observation or questionnaires to capture time required f
Conditions Studied
Interventions
- BEHAVIORAL CATCH-IT
- BEHAVIORAL TEAMS
Study Locations (1)
Illinois
- UI Health - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 636 participants |
| Start Date | 2020-01-01 |
| Est. Completion | 2026-10-01 |
| Phase | NA |
What the registry record for NCT04290754 still lists
NCT04290754 is an interventional study that assigns participants to a tested intervention. The registered 636 participants enrollment target is mid-sized for trials with a published cap, below the 785-participant average among 679 other Depression trials with a reported enrollment target (19% lower).
The record links to 1 condition, with Depression appearing as the primary indexed condition, and to 2 interventions - of which CATCH-IT is the first listed.
NCT04290754 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04290754 about?
NCT04290754 is a clinical study titled "PATH 2 Purpose: Primary Care and Community-Based Prevention of Mental Disorders in Adolescents". PATH (Promoting AdolescenT Health) 2 Purpose is a two-arm comparative effectiveness research trial to that will evaluate the ability of the interventions, Competent Adulthood Transition with Cognitive-behavioral \& Interpersonal Training (CATCH-IT) and Teens Achieving Mastery over Stress (TEAMS), to...
What is the current status of trial NCT04290754?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 636 participants. The study started on 2020-01-01. Estimated completion is 2026-10-01.
What conditions does trial NCT04290754 study?
This clinical trial studies the following conditions: Depression.
What interventions are being tested in trial NCT04290754?
The interventions under investigation include: CATCH-IT (BEHAVIORAL), TEAMS (BEHAVIORAL).
Who is sponsoring clinical trial NCT04290754?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04290754 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04290754's enrollment target sits among peer trials
636 65th of 679 higher than 615 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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