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NCT04188548 · ClinicalTrials.gov registry record · Phase 1

A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer

A Phase 1 study of Breast Cancer and Endometrial Cancer, sponsored by Eli Lilly and Company.

Active
Registry status
Phase 1
Development phase
500
Enrollment target
20
Study locations

NCT04188548 is a Phase 1 study of Breast Cancer and Endometrial Cancer that is active but no longer recruiting, run by Eli Lilly and Company. The registered enrollment target is 500 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (82% lower). The trial reports 20 study locations across 12 states.

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The verdict

NCT04188548, a Phase 1 study of Breast Cancer and Endometrial Cancer, is active but no longer recruiting, sponsored by Eli Lilly and Company.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
500 participants
Enrollment target
20
Study locations

Study Summary

The reason for this study is to see if the study drug LY3484356 alone or in combination with other anticancer therapies is safe and effective in participants with advanced or metastatic breast cancer or endometrial cancer.

Interventions

  • DRUG Trastuzumab
  • DRUG Everolimus
  • DRUG Abemaciclib
  • DRUG Alpelisib
  • DRUG LY3484356

Study Locations (20)

California

  • Beverly Hills Cancer Center - Beverly Hills
  • University of California, Irvine - Orange
  • UCSF Medical Center at Mission Bay - San Francisco

New York

  • Memorial Sloan Kettering Cancer Center - Commack
  • Memorial Sloan Kettering Cancer Center - New York
  • Wilmot Cancer Institute - Rochester

Arizona

  • Banner MD Anderson Cancer Center - Gilbert
  • Mayo Clinic in Arizona - Phoenix - Phoenix

Florida

  • Mayo Clinic in Florida - Jacksonville
  • Lake Nona DDU - Orlando

Massachusetts

  • Massachusetts General Hospital - Boston
  • Dana-Farber Cancer Institute - Boston

Minnesota

  • Minnesota Oncology/Hematology PA - Minneapolis
  • Mayo Clinic - Rochester

Arkansas

  • Highlands Oncology Group - Springdale

Georgia

  • Winship Cancer Center Emory University - Atlanta

Trial Details

FieldValue
Enrollment Target 500 participants
Start Date 2019-12-10
Est. Completion 2027-12
Phase Phase 1

Sponsor

Eli Lilly and Company

1,341 total trials

What the Registry Record Tells You About NCT04188548

The ClinicalTrials.gov registry entry for NCT04188548 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (82% lower). The listed sponsor is Eli Lilly and Company, which has 1,341 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Breast Cancer appearing as the primary indexed condition, and to 5 interventions - of which Trastuzumab is the first listed.

NCT04188548 reports 20 study locations spanning 12 distinct geographic areas - top geographies include California, New York, Arizona.

Frequently Asked Questions

What is clinical trial NCT04188548 about?

NCT04188548 is a clinical study titled "A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer". The reason for this study is to see if the study drug LY3484356 alone or in combination with other anticancer therapies is safe and effective in participants with advanced or metastatic breast cancer or endometrial cancer.

What is the current status of trial NCT04188548?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 500 participants. The study started on 2019-12-10. Estimated completion is 2027-12.

What conditions does trial NCT04188548 study?

This clinical trial studies the following conditions: Breast Cancer, Endometrial Cancer, Metastatic Breast Cancer, Advanced Breast Cancer.

What interventions are being tested in trial NCT04188548?

The interventions under investigation include: Trastuzumab (DRUG), Everolimus (DRUG), Abemaciclib (DRUG), Alpelisib (DRUG), LY3484356 (DRUG).

Who is sponsoring clinical trial NCT04188548?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04188548 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.