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NCT04187105 · ClinicalTrials.gov registry record · Phase 2
BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)
A Phase 2 study of Acute Leukemia and MDS, sponsored by University of Illinois at Chicago.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 27
- Enrollment target
- 1
- Study location
NCT04187105: Recruiting Phase 2 study of Acute Leukemia and MDS, sponsored by University of Illinois at Chicago.
NCT04187105 is a Phase 2 study of Acute Leukemia and MDS that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 27 participants, below the 462-participant average among 37 other Acute Leukemia trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04187105, a Phase 2 study of Acute Leukemia and MDS, is actively recruiting participants, sponsored by University of Illinois at Chicago.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 27 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is being done to see if the addition of a targeted form of radiation to standard conditioning regimen will increase the amount of cancer cells that are killed off in the bone marrow and reduce the chances that your disease may return. This description is called Intensity Modulated Total Marrow Irradiation (IM-TMI).
Primary Outcome
To evaluate the number of patients with acute leukemia or MDS who are GVHD-free, relapse free (GRFS) after 1 year of undergoing undergoing a treatment regimen of haploidentical stem cell transplant with conditioning and total marrow irradiation.
Conditions Studied
Interventions
- RADIATION Conditioning regimen with half-matched (haploidentical) stem cell transplant
- DRUG Conditioning regimen with half-matched (haploidentical) stem cell transplant
- DEVICE Conditioning regimen with half-matched (haploidentical) stem cell transplant
- OTHER Conditioning regimen with half-matched (haploidentical) stem cell transplant
Study Locations (1)
Illinois
- University of Illinois Cancer Center - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 27 participants |
| Start Date | 2020-01-27 |
| Est. Completion | 2026-12 |
| Phase | Phase 2 |
What NCT04187105 shows while recruiting
NCT04187105 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 462-participant average among 37 other Acute Leukemia trials with a reported enrollment target (94% lower).
The record links to 2 conditions, with Acute Leukemia appearing as the primary indexed condition, and to 4 interventions - of which Conditioning regimen with half-matched (haploidentical) stem cell transplant is the first listed.
NCT04187105 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04187105 about?
NCT04187105 is a clinical study titled "BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)". This study is being done to see if the addition of a targeted form of radiation to standard conditioning regimen will increase the amount of cancer cells that are killed off in the bone marrow and reduce the chances that your disease may return. This description is called Intensity Modulated Total M...
What is the current status of trial NCT04187105?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 27 participants. The study started on 2020-01-27. Estimated completion is 2026-12.
What conditions does trial NCT04187105 study?
This clinical trial studies the following conditions: Acute Leukemia, MDS.
What interventions are being tested in trial NCT04187105?
The interventions under investigation include: Conditioning regimen with half-matched (haploidentical) stem cell transplant (RADIATION), Conditioning regimen with half-matched (haploidentical) stem cell transplant (DRUG), Conditioning regimen with half-matched (haploidentical) stem cell transplant (DEVICE), Conditioning regimen with half-matched (haploidentical) stem cell transplant (OTHER).
Who is sponsoring clinical trial NCT04187105?
This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04187105 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04187105's enrollment target sits among peer trials
27 30th of 37 higher than 7 of 37 other Acute Leukemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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