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NCT04145011 · ClinicalTrials.gov registry record · NA
Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain
A NA study of Osteoarthritis of the Knee, sponsored by Avanos Medical.
- Completed
- Registry status
- NA
- Development phase
- 153
- Enrollment target
- 7
- Study locations
NCT04145011: Completed NA study of Osteoarthritis of the Knee, sponsored by Avanos Medical.
NCT04145011 is a NA study of Osteoarthritis of the Knee that has completed, run by Avanos Medical. The registered enrollment target is 153 participants, below the 203-participant average among 16 other Osteoarthritis of the Knee trials with a reported enrollment target (25% lower). The trial reports 7 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04145011, a NA study of Osteoarthritis of the Knee, has completed, sponsored by Avanos Medical.
- COMPLETED
- Registry status
- NA
- Development phase
- 153 participants
- Enrollment target
- 7
- Study locations
Study Summary
This study is being performed to assess the relative effectiveness of genicular nerve ablation with the COOLIEF\* Cooled Radiofrequency probe to manage moderate to severe knee pain in patients with osteoarthritis (OA) of the knee when compared to radiofrequency ablation using a Standard Radiofrequency probe.
Primary Outcome
The proportion of subjects whose knee pain is reduced by ≥ 50% based on the NRS. The NRS is an 11-point scale (0 points to 10 points), where 0 points equals "no pain" and 10 points equals "worst pain". There are no sub-scales.
Conditions Studied
Interventions
- DEVICE Cooled Radiofrequency
- DEVICE Standard Radiofrequency
Study Locations (7)
Pennsylvania
- University Orthopedics Center - Altoona
- Pain Diagnostics and Interventional Care - Sewickley
- University Orthopedics Center - State College
South Carolina
- Piedmont Comprehensive Pain Management - Anderson
Utah
- University of Utah - Salt Lake City
Virginia
- University of Virginia - Charlottesville
West Virginia
- The Spine and Nerve Centers of St. Francis Hosptial - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 153 participants |
| Start Date | 2019-10-04 |
| Est. Completion | 2022-10-10 |
| Phase | NA |
What the finished NCT04145011 record still lists
NCT04145011 is an interventional study that assigns participants to a tested intervention. The registered 153 participants enrollment target is mid-sized for trials with a published cap, below the 203-participant average among 16 other Osteoarthritis of the Knee trials with a reported enrollment target (25% lower).
The record links to 1 condition, with Osteoarthritis of the Knee appearing as the primary indexed condition, and to 2 interventions - of which Cooled Radiofrequency is the first listed.
NCT04145011 lists 7 locations in 5 states (Pennsylvania, South Carolina, Utah).
Frequently Asked Questions
What is clinical trial NCT04145011 about?
NCT04145011 is a clinical study titled "Coolief Cooled Radiofrequency vs. Conventional Radiofrequency to Manage OA Knee Pain". This study is being performed to assess the relative effectiveness of genicular nerve ablation with the COOLIEF\* Cooled Radiofrequency probe to manage moderate to severe knee pain in patients with osteoarthritis (OA) of the knee when compared to radiofrequency ablation using a Standard Radiofrequen...
What is the current status of trial NCT04145011?
This trial is currently completed. It is a NA study. The enrollment target is 153 participants. The study started on 2019-10-04. Estimated completion is 2022-10-10.
What conditions does trial NCT04145011 study?
This clinical trial studies the following conditions: Osteoarthritis of the Knee.
What interventions are being tested in trial NCT04145011?
The interventions under investigation include: Cooled Radiofrequency (DEVICE), Standard Radiofrequency (DEVICE).
Who is sponsoring clinical trial NCT04145011?
This trial is sponsored by Avanos Medical, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04145011 being conducted?
This trial has 7 study locations across Pennsylvania, South Carolina, Utah, Virginia, West Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Osteoarthritis of the Knee
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04145011's enrollment target sits among peer trials
153 10th of 16 higher than 7 of 16 other Osteoarthritis of the Knee trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Osteoarthritis of the Knee trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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