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Growth Hormone Deficiency clinical trials
Every US clinical trial registered for Growth Hormone Deficiency — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
17 US clinical trials · 5 currently recruiting
The research picture
Growth Hormone Deficiency has 17 registered US clinical trials, 5 of them open to new participants right now — about 29% of the total.
- 5
- recruiting participants now
- 29%
- of trials open to enrollment
- 6
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Ascendis Pharma Endocrinology Division A/S
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Chromosome 18 Clinical Research Center
The University of Texas Health Science Center at San Antonio
NCT00227253
A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA
Ascendis Pharma Endocrinology Division A/S
NCT05820672
A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin
Ascendis Pharma Endocrinology Division A/S
NCT05775523
Growth Hormone Replacement Therapy for Retried Professional Football Players
Center for Neurological Studies
NCT04121780
Effects of GH and Lirglutide on AgRP
Columbia University
NCT05681299
A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency
Ascendis Pharma Endocrinology Division A/S
NCT04615273
Genotropin Study Assessing Use of Injection Pen
Pfizer
NCT00965484
Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency
Massachusetts General Hospital
NCT00182091
VRS-317 in Adult Subjects With Growth Hormone Deficiency
Versartis
NCT01359488
Pharmacokinetics and Pharmacodynamics of Long Acting Human Growth Hormone (hGH) Product (MOD-4023) in Healthy Caucasian and Japanese Volunteers
OPKO Health
NCT02418767
Testosterone and Growth Hormone for Bone Loss in Men
University of Pennsylvania
NCT00080483
Cardiovascular Risk in Growth Hormone Deficient Young Adult Males After Completing Growth Hormone Therapy
Children's Mercy Hospital Kansas City
NCT00711061
Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia
Children's Hospital Los Angeles
NCT00140413
Growth Hormone and Chromosome 18q- and Abnormal Growth
The University of Texas Health Science Center at San Antonio
NCT00134420
Phase 2 Study of LUM-201 in Children Who Have Previously Completed the LUM-201-01 Trial (OraGrowtH213)
Lumos Pharma
NCT05250063
A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood
Oregon Health and Science University
NCT00212758
Low Dose Growth Hormone (GH) on Insulin Sensitivity and Cortisol Production Rates
Oregon Health and Science University
NCT00517062
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 3 |
| Phase 3 | 3 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Growth Hormone Deficiency Trial Landscape
ClinicalTrials.gov lists 17 US studies indexed under Growth Hormone Deficiency, and 5 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Growth Hormone Deficiency shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 6 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Growth Hormone Deficiency is led by Ascendis Pharma Endocrinology Division A/S with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 17 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Growth Hormone Deficiency?
PlainTrial tracks 17 US clinical trials for Growth Hormone Deficiency, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Growth Hormone Deficiency?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.