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ClinicalTrials.gov 5 recruiting now official registry

Growth Hormone Deficiency clinical trials

5 of 17 indexed Growth Hormone Deficiency trials are currently recruiting.

17 US clinical trials · 5 currently recruiting

Growth Hormone Deficiency is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Ascendis Pharma Endocrinology Division A/S, running 3 of these trials.

The research picture

Growth Hormone Deficiency has 17 registered US clinical trials, 5 of them open to new participants right now, about 29% of the total.

5
recruiting participants now
29%
of trials open to enrollment
6
in Phase 3–4 (later-stage)
3
top sponsor: Ascendis Pharma Endocrinology Division A/S
Phase 13Phase 23Phase 33Phase 43

Active & Recent Trials

17 total, page 1 of 1

RECRUITING 4,000 participants

Chromosome 18 Clinical Research Center

The University of Texas Health Science Center at San Antonio

NCT00227253

RECRUITING 900 participants

A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA

Ascendis Pharma Endocrinology Division A/S

NCT05820672

RECRUITING 500 participants

A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin

Ascendis Pharma Endocrinology Division A/S

NCT05775523

RECRUITING Phase 2 42 participants

Growth Hormone Replacement Therapy for Retried Professional Football Players

Center for Neurological Studies

NCT04121780

RECRUITING Phase 4 40 participants

Effects of GH and Lirglutide on AgRP

Columbia University

NCT05681299

COMPLETED Phase 3 264 participants

A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency

Ascendis Pharma Endocrinology Division A/S

NCT04615273

COMPLETED Phase 3 136 participants

Genotropin Study Assessing Use of Injection Pen

Pfizer

NCT00965484

COMPLETED NA 75 participants

Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Deficiency

Massachusetts General Hospital

NCT00182091

COMPLETED Phase 1 50 participants

VRS-317 in Adult Subjects With Growth Hormone Deficiency

Versartis

NCT01359488

COMPLETED Phase 1 42 participants

Pharmacokinetics and Pharmacodynamics of Long Acting Human Growth Hormone (hGH) Product (MOD-4023) in Healthy Caucasian and Japanese Volunteers

OPKO Health

NCT02418767

COMPLETED Phase 2 35 participants

Testosterone and Growth Hormone for Bone Loss in Men

University of Pennsylvania

NCT00080483

COMPLETED 24 participants

Cardiovascular Risk in Growth Hormone Deficient Young Adult Males After Completing Growth Hormone Therapy

Children's Mercy Hospital Kansas City

NCT00711061

COMPLETED Phase 4 20 participants

Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia

Children's Hospital Los Angeles

NCT00140413

COMPLETED Phase 3 20 participants

Growth Hormone and Chromosome 18q- and Abnormal Growth

The University of Texas Health Science Center at San Antonio

NCT00134420

COMPLETED Phase 2 18 participants

Phase 2 Study of LUM-201 in Children Who Have Previously Completed the LUM-201-01 Trial (OraGrowtH213)

Lumos Pharma

NCT05250063

COMPLETED Phase 4 17 participants

A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in Blood

Oregon Health and Science University

NCT00212758

COMPLETED Early Phase 1 16 participants

Low Dose Growth Hormone (GH) on Insulin Sensitivity and Cortisol Production Rates

Oregon Health and Science University

NCT00517062

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3
Phase 3 3
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Growth Hormone Deficiency Trial Landscape

17 indexed Growth Hormone Deficiency studies · 5 recruiting (29%).

Phase mix: 6 late (III/IV) vs 6 early (I/II).

Top sponsor: Ascendis Pharma Endocrinology Division A/S (3 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Growth Hormone Deficiency?

PlainTrial tracks 17 US clinical trials for Growth Hormone Deficiency, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Growth Hormone Deficiency?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.