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NCT04050735 · ClinicalTrials.gov registry record · NA
Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection
A NA study of Alcohol Drinking and HIV-1-infection, sponsored by Brown University.
- Completed
- Registry status
- NA
- Development phase
- 76
- Enrollment target
- 1
- Study location
NCT04050735: Completed NA study of Alcohol Drinking and HIV-1-infection, sponsored by Brown University.
NCT04050735 is a NA study of Alcohol Drinking and HIV-1-infection that has completed, run by Brown University. The registered enrollment target is 76 participants, below the 630-participant average among 85 other Alcohol Drinking trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04050735, a NA study of Alcohol Drinking and HIV-1-infection, has completed, sponsored by Brown University.
- COMPLETED
- Registry status
- NA
- Development phase
- 76 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine whether moderate alcohol use in the context of HIV infection exacerbates inflammatory signaling in the immune system and brain. The study will recruit healthy individuals and people living with HIV infection who are otherwise in good health to participate. Participants will complete an experimental protocol that involves controlled alcohol administration and magnetic resonance imaging (MRI). Primary outcomes are plasma biomarkers of inflammation and MRI markers correlated with neuroinflammation. Results will advance understanding of the effects of alcohol use in people living with HIV infection.
Primary Outcome
Lipopolysaccharide (LPS), measured in pg/ml
Conditions Studied
Interventions
- OTHER Placebo
- OTHER Alcohol, ethyl, moderate dose
Study Locations (1)
Rhode Island
- Brown University and The Miriam Hospital - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2021-05-19 |
| Est. Completion | 2024-07-02 |
| Phase | NA |
What the finished NCT04050735 record still lists
NCT04050735 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 630-participant average among 85 other Alcohol Drinking trials with a reported enrollment target (88% lower).
The record links to 2 conditions, with Alcohol Drinking appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT04050735 reports a single indexed study location in Rhode Island.
Frequently Asked Questions
What is clinical trial NCT04050735 about?
NCT04050735 is a clinical study titled "Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection". This study will examine whether moderate alcohol use in the context of HIV infection exacerbates inflammatory signaling in the immune system and brain. The study will recruit healthy individuals and people living with HIV infection who are otherwise in good health to participate. Participants will c...
What is the current status of trial NCT04050735?
This trial is currently completed. It is a NA study. The enrollment target is 76 participants. The study started on 2021-05-19. Estimated completion is 2024-07-02.
What conditions does trial NCT04050735 study?
This clinical trial studies the following conditions: Alcohol Drinking, HIV-1-infection.
What interventions are being tested in trial NCT04050735?
The interventions under investigation include: Placebo (OTHER), Alcohol, ethyl, moderate dose (OTHER).
Who is sponsoring clinical trial NCT04050735?
This trial is sponsored by Brown University, which has 231 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04050735 being conducted?
This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04050735's enrollment target sits among peer trials
76 62nd of 85 higher than 24 of 85 other Alcohol Drinking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alcohol Drinking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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