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NCT03998748 · ClinicalTrials.gov registry record · NA
Electrophysiological Correlates of Cognition in Depression
A NA study, sponsored by Mclean Hospital.
- Terminated
- Registry status
- NA
- Development phase
- 80
- Enrollment target
NCT03998748 is a NA study that was terminated before completion, run by Mclean Hospital. The registered enrollment target is 80 participants.
The verdict
NCT03998748, a NA study, was terminated before completion, sponsored by Mclean Hospital.
- TERMINATED
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
Study Summary
Biogenetic messages about the etiology of mental illness (e.g., the "chemical imbalance theory" of depression) are increasing but the impact that these have on decision-making and motivation is not yet clear. This study will evaluate the impact of biogenetic feedback on cognitive control and default-mode network functioning, as well as motivation for different psychiatric treatment modalities. Participants with major depressive disorder (MDD) will be instructed that they are being tested for genetic susceptibility to depression and will be randomized to receive feedback that they either do or do not have a genetic predisposition to depression. Before and after receiving this feedback, brain activity will be assessed using high-density electroencephalogram (EEG). The investigators hypothesize that those exposed to the genetic feedback condition will evidence heightened ruminative default mode network activity and perceive medications to be more effective than psychotherapy.
Interventions
- OTHER Sham Genetic Feedback
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2019-10-08 |
| Est. Completion | 2022-08-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03998748
The ClinicalTrials.gov registry entry for NCT03998748 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mclean Hospital, which has 140 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Sham Genetic Feedback is the first listed.
NCT03998748 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT03998748 about?
NCT03998748 is a clinical study titled "Electrophysiological Correlates of Cognition in Depression". Biogenetic messages about the etiology of mental illness (e.g., the "chemical imbalance theory" of depression) are increasing but the impact that these have on decision-making and motivation is not yet clear. This study will evaluate the impact of biogenetic feedback on cognitive control and default...
What is the current status of trial NCT03998748?
This trial is currently terminated. It is a NA study. The enrollment target is 80 participants. The study started on 2019-10-08. Estimated completion is 2022-08-01.
What interventions are being tested in trial NCT03998748?
The interventions under investigation include: Sham Genetic Feedback (OTHER).
Who is sponsoring clinical trial NCT03998748?
This trial is sponsored by Mclean Hospital, which has 140 total clinical trials registered on ClinicalTrials.gov.
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