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NCT03981575 · ClinicalTrials.gov registry record

Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

A clinical trial of Myotonic Dystrophy 1 and DM1, sponsored by Virginia Commonwealth University.

Recruiting
Registry status
700
Enrollment target
17
Study locations

NCT03981575 is a study of Myotonic Dystrophy 1 and DM1 that is actively recruiting participants, run by Virginia Commonwealth University. The registered enrollment target is 700 participants, below the 938-participant average among 4 other Myotonic Dystrophy 1 trials with a reported enrollment target (25% lower). The trial reports 17 study locations across 10 states.

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The verdict

NCT03981575, a study of Myotonic Dystrophy 1 and DM1, is actively recruiting participants, sponsored by Virginia Commonwealth University.

RECRUITING
Registry status
700 participants
Enrollment target
17
Study locations

Study Summary

Building on previous work of the Myotonic Dystrophy Clinical Research Network (DMCRN), the present study seeks to overcome insufficient data on natural history; lack of reliable biomarkers; and incomplete characterization and limited biological understanding of the phenotypic heterogeneity of Myotonic Dystrophy 1 by examining strategies to improve the reliability by making further refinements in our sample collection and analysis procedures by developing strategies for managing patient heterogeneity going forward. Funding Source- FDA OOPD

Conditions Studied

Myotonic Dystrophy 1 DM1

Study Locations (17)

Other

  • Université de Sherbrooke - Québec
  • Friedrich Baur Institute, Ludwig-Maximilians-Universität München - München
  • Centro Clinico NeMO - Milan
  • Radboud University Medical Center - Nijmegen
  • University of Auckland - Auckland
  • St. George's, University of London - London
  • University College London - London

California

  • University of California, San Diego - La Jolla
  • University of California, Los Angeles - Los Angeles

Colorado

  • University of Colorado - Denver - Denver

Florida

  • University of Florida - Gainesville

Iowa

  • University of Iowa - Iowa City

Kansas

  • Kansas University Medical Center - Kansas City

New York

  • University of Rochester - Rochester

Ohio

  • Ohio State University - Columbus

Trial Details

FieldValue
Enrollment Target 700 participants
Start Date 2019-01-01
Est. Completion 2026-12-01

Sponsor

Virginia Commonwealth University

558 total trials

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What the Registry Record Tells You About NCT03981575

The ClinicalTrials.gov registry entry for NCT03981575 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 700 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 938-participant average among 4 other Myotonic Dystrophy 1 trials with a reported enrollment target (25% lower). The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Myotonic Dystrophy 1 appearing as the primary indexed condition, and to 0 interventions.

NCT03981575 reports 17 study locations spanning 10 distinct geographic areas - top geographies include Other, California, Colorado.

Frequently Asked Questions

What is clinical trial NCT03981575 about?

NCT03981575 is a clinical study titled "Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)". Building on previous work of the Myotonic Dystrophy Clinical Research Network (DMCRN), the present study seeks to overcome insufficient data on natural history; lack of reliable biomarkers; and incomplete characterization and limited biological understanding of the phenotypic heterogeneity of Myoton...

What is the current status of trial NCT03981575?

This trial is currently recruiting. The enrollment target is 700 participants. The study started on 2019-01-01. Estimated completion is 2026-12-01.

What conditions does trial NCT03981575 study?

This clinical trial studies the following conditions: Myotonic Dystrophy 1, DM1.

Who is sponsoring clinical trial NCT03981575?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03981575 being conducted?

This trial has 17 study locations across California, Colorado, Florida, Iowa, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.