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NCT03960827 · ClinicalTrials.gov registry record · NA
Molecular Transducers of Physical Activity Consortium
A NA study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- NA
- Development phase
- 1,837
- Enrollment target
NCT03960827: Completed NA study, sponsored by Wake Forest University Health Sciences.
NCT03960827 is a NA study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 1,837 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (31% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03960827, a NA study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- NA
- Development phase
- 1,837 participants
- Enrollment target
Study Summary
The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, a mechanistic randomized controlled trial (RCT) is conducted, in which adult study participants are randomized to endurance exercise (EE) training, resistance exercise (RE) training, or no exercise Control for a period of approximately 12 weeks. The overarching hypothesis is that there are discoverable molecular transducers that communicate and coordinate the effects of exercise on cells, tissues, and organs, which may initiate processes ultimately leading to the health benefits of exercise. Because this is a mechanistic trial, the main goal is not a single health-related outcome. Rather, the goal is to generate a resource leading to the generation of a map of the molecular responses to exercise that will be used by the Consortium and by the scientific community at large to generate hypotheses for future investigations of the health benefits of PA.
Primary Outcome
Changes in log-transformed CPET VO2 Peak calculated as L/min
Interventions
- OTHER EE Training
- OTHER RE Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,837 participants |
| Start Date | 2019-08-28 |
| Est. Completion | 2025-05-31 |
| Phase | NA |
What the finished NCT03960827 record still lists
NCT03960827 is an interventional study that assigns participants to a tested intervention. Its 1,837 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (31% higher).
The record links to 0 conditions, and to 2 interventions - of which EE Training is the first listed.
NCT03960827 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03960827 about?
NCT03960827 is a clinical study titled "Molecular Transducers of Physical Activity Consortium". The goal of the Molecular Transducers of Physical Activity Consortium (MoTrPAC) is to assess molecular changes that occur in response to physical activity (PA). To achieve this aim, a mechanistic randomized controlled trial (RCT) is conducted, in which adult study participants are randomized to endu...
What is the current status of trial NCT03960827?
This trial is currently completed. It is a NA study. The enrollment target is 1,837 participants. The study started on 2019-08-28. Estimated completion is 2025-05-31.
What interventions are being tested in trial NCT03960827?
The interventions under investigation include: EE Training (OTHER), RE Training (OTHER).
Who is sponsoring clinical trial NCT03960827?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03960827's enrollment target sits among peer trials
1,837 57th of 2000 higher than 1,944 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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