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RECRUITING Phase 3

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

NCT06740630 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess the consistency of immune response to three different lots of GSK's investigational varicella vaccine (VNS Vaccine), and to compare the safety and immune response of VNS vaccine to an already approved varicella vaccine (VV) known as Varivax. The study will be conducted in healthy children aged 12 to 15 months, who have neither contracted varicella nor received a varicella vaccination.

Conditions Studied

Interventions

  • BIOLOGICAL Investigational varicella vaccine_Lot 1
  • BIOLOGICAL Investigational varicella vaccine_Lot 2
  • BIOLOGICAL Investigational varicella vaccine_Lot 3
  • BIOLOGICAL Marketed varicella vaccine_Lot 1
  • BIOLOGICAL Marketed varicella vaccine_Lot 2

Study Locations (5)

Utah

  • GSK Investigational Site — Layton
  • GSK Investigational Site — Layton

Florida

  • GSK Investigational Site — Tampa

Michigan

  • GSK Investigational Site — Bingham Farms

Texas

  • GSK Investigational Site — McAllen

Trial Details

FieldValue
Enrollment Target 1,840 participants
Start Date 2025-01-10
Est. Completion 2027-05-13
Phase Phase 3

Sponsor

GlaxoSmithKline

558 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06740630

The ClinicalTrials.gov registry entry for NCT06740630 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 1,840 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Chickenpox appearing as the primary indexed condition, and to 5 interventions — of which Investigational varicella vaccine_Lot 1 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06740630 reports 5 study locations spanning 4 distinct geographic areas — top geographies include Utah, Florida, Michigan. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06740630 about?

NCT06740630 is a clinical study titled "A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age". The purpose of this study is to assess the consistency of immune response to three different lots of GSK's investigational varicella vaccine (VNS Vaccine), and to compare the safety and immune response of VNS vaccine to an already approved varicella vaccine (VV) known as Varivax. The study will be c...

What is the current status of trial NCT06740630?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 1,840 participants. The study started on 2025-01-10. Estimated completion is 2027-05-13.

What conditions does trial NCT06740630 study?

This clinical trial studies the following conditions: Chickenpox. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06740630?

The interventions under investigation include: Investigational varicella vaccine_Lot 1 (BIOLOGICAL), Investigational varicella vaccine_Lot 2 (BIOLOGICAL), Investigational varicella vaccine_Lot 3 (BIOLOGICAL), Marketed varicella vaccine_Lot 1 (BIOLOGICAL), Marketed varicella vaccine_Lot 2 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06740630?

This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06740630 being conducted?

This trial has 5 study locations across Florida, Michigan, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial