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NCT03955978 · ClinicalTrials.gov registry record · Phase 1
TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer
A Phase 1 study of Endometrial Cancer and Cancer of the Endometrium, sponsored by Washington University School of Medicine.
- Active
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT03955978 is a Phase 1 study of Endometrial Cancer and Cancer of the Endometrium that is active but no longer recruiting, run by Washington University School of Medicine. The registered enrollment target is 10 participants, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT03955978, a Phase 1 study of Endometrial Cancer and Cancer of the Endometrium, is active but no longer recruiting, sponsored by Washington University School of Medicine.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with inoperable endometrial cancer have limited treatment options. PD-L1 expression is common in endometrial cancers and RT induces tumor and systemic changes that induce the immune system. The purpose of this trial is to evaluate anti-PD-1/PD-L1 axis therapy in conjunction of standard of care RT for patients with inoperable endometrial cancer in order to establish the safety and efficacy of inducing an anti-tumor immune response.
Conditions Studied
Interventions
- RADIATION Brachytherapy
- DRUG TSR-042
- PROCEDURE Endometrial biopsy
- PROCEDURE Blood draw for immune response
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2019-10-15 |
| Est. Completion | 2029-02-01 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03955978
The ClinicalTrials.gov registry entry for NCT03955978 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 524-participant average among 181 other Endometrial Cancer trials with a reported enrollment target (98% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Endometrial Cancer appearing as the primary indexed condition, and to 4 interventions - of which Brachytherapy is the first listed.
NCT03955978 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.
Frequently Asked Questions
What is clinical trial NCT03955978 about?
NCT03955978 is a clinical study titled "TSR-042 in Addition to Standard of Care Definitive Radiation for Inoperable Endometrial Cancer". Patients with inoperable endometrial cancer have limited treatment options. PD-L1 expression is common in endometrial cancers and RT induces tumor and systemic changes that induce the immune system. The purpose of this trial is to evaluate anti-PD-1/PD-L1 axis therapy in conjunction of standard of c...
What is the current status of trial NCT03955978?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2019-10-15. Estimated completion is 2029-02-01.
What conditions does trial NCT03955978 study?
This clinical trial studies the following conditions: Endometrial Cancer, Cancer of the Endometrium.
What interventions are being tested in trial NCT03955978?
The interventions under investigation include: Brachytherapy (RADIATION), TSR-042 (DRUG), Endometrial biopsy (PROCEDURE), Blood draw for immune response (PROCEDURE).
Who is sponsoring clinical trial NCT03955978?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03955978 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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