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NCT03893682 · ClinicalTrials.gov registry record · Phase 1

A Study of CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas

A Phase 1 study, sponsored by Aptose Biosciences.

Terminated
Registry status
Phase 1
Development phase
36
Enrollment target

NCT03893682: Clinical Trial Phase 1 study, sponsored by Aptose Biosciences.

NCT03893682 is a Phase 1 study that was terminated before completion, run by Aptose Biosciences. The registered enrollment target is 36 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03893682, a Phase 1 study, was terminated before completion, sponsored by Aptose Biosciences.

TERMINATED
Registry status
Phase 1
Development phase
36 participants
Enrollment target

Study Summary

This study is being done to evaluate the safety, tolerability and effectiveness of Oral CG-806 for the treatment of patients with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or Non-Hodgkin's Lymphomas who have failed or are intolerant to two or more lines of established therapy or for whom no other treatment options are available.

Primary Outcome

To determine the safety and tolerability of CG-806.

Interventions

  • DRUG CG-806

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2019-04-30
Est. Completion 2024-05-17
Phase Phase 1
Aptose Biosciences

7 total trials

Why NCT03893682 stopped before completion

NCT03893682 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (40% lower).

The record links to 0 conditions, and to 1 intervention - of which CG-806 is the first listed.

NCT03893682 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03893682 about?

NCT03893682 is a clinical study titled "A Study of CG-806 in Patients With Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas". This study is being done to evaluate the safety, tolerability and effectiveness of Oral CG-806 for the treatment of patients with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or Non-Hodgkin's Lymphomas who have failed or are intolerant to two or more lines of established the...

What is the current status of trial NCT03893682?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2019-04-30. Estimated completion is 2024-05-17.

What interventions are being tested in trial NCT03893682?

The interventions under investigation include: CG-806 (DRUG).

Who is sponsoring clinical trial NCT03893682?

This trial is sponsored by Aptose Biosciences, which has 7 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03893682's enrollment target sits among peer trials

36 1210th of 2000 higher than 743 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03893682, the US trial registry maintained by the National Library of Medicine. NCT03893682 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.