Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03822182 · ClinicalTrials.gov registry record · Phase 4
Single Shot Liposomal Bupivicaine in Rotator Cuff Surgery
A Phase 4 study of Pain, Postoperative and Rotator Cuff Tear, sponsored by Indiana University.
- Completed
- Registry status
- Phase 4
- Development phase
- 78
- Enrollment target
- 1
- Study location
NCT03822182: Completed Phase 4 study of Pain, Postoperative and Rotator Cuff Tear, sponsored by Indiana University.
NCT03822182 is a Phase 4 study of Pain, Postoperative and Rotator Cuff Tear that has completed, run by Indiana University. The registered enrollment target is 78 participants, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03822182, a Phase 4 study of Pain, Postoperative and Rotator Cuff Tear, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 78 participants
- Enrollment target
- 1
- Study location
Study Summary
This document is a protocol for a human research study. This study is to be conducted according to United States standards of Good Clinical Practice in accordance with applicable Federal regulations and institutional research policies and procedures. Liposomal bupivacaine (LB) has been shown to decrease post-operative pain and narcotic use when administered perioperatively as a local injection during arthroplasty procedures. Studies have also demonstrated that LB used in conjunction with dexamethasone may increase the duration of effectiveness of LB. This study seeks to evaluate if there is a difference in post-operative pain and narcotic use when LB is administered in an interscalene block during outpatient rotator cuff repair surgery. Furthermore, this study aims to determine if the addition of dexamethasone with LB results in a prolonged decrease in post-operative pain and a reduction in narcotic use.
Primary Outcome
Patient-reported post-operative VAS pain (on a scale of 0-10 with zero implying no pain and 10 indicating severe pain), measured post operatively, in 8-hour increments, for a total of 96 hours post-surgery, Patients will be prompted via text message to provide VAS pain every 8 hours. If a response text message is not received, a phone call will be made to obtain the information. Patients who do not have a smart phone will receive a phone call or keep a personal log of VAS pain.
Conditions Studied
Interventions
- DRUG Dexamethasone
- DRUG liposomal bupivicaine
Study Locations (1)
Indiana
- American Health Network - Avon
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 78 participants |
| Start Date | 2018-10-24 |
| Est. Completion | 2020-01-22 |
| Phase | Phase 4 |
What the finished NCT03822182 record still lists
NCT03822182 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 78 participants, a relatively small participant target, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (71% lower).
The record links to 2 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 2 interventions - of which Dexamethasone is the first listed.
NCT03822182 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT03822182 about?
NCT03822182 is a clinical study titled "Single Shot Liposomal Bupivicaine in Rotator Cuff Surgery". This document is a protocol for a human research study. This study is to be conducted according to United States standards of Good Clinical Practice in accordance with applicable Federal regulations and institutional research policies and procedures. Liposomal bupivacaine (LB) has been shown to dec...
What is the current status of trial NCT03822182?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 78 participants. The study started on 2018-10-24. Estimated completion is 2020-01-22.
What conditions does trial NCT03822182 study?
This clinical trial studies the following conditions: Pain, Postoperative, Rotator Cuff Tear.
What interventions are being tested in trial NCT03822182?
The interventions under investigation include: Dexamethasone (DRUG), liposomal bupivicaine (DRUG).
Who is sponsoring clinical trial NCT03822182?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03822182 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain, Postoperative
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03822182's enrollment target sits among peer trials
78 62nd of 113 higher than 51 of 113 other Pain, Postoperative trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Postoperative trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia
RECRUITING · Phase 4
-
Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
RECRUITING · Phase 4
-
The Effect of Zolpidem on Outcomes Following Lumbar Spine Fusion
RECRUITING · Phase 4
-
Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial
RECRUITING · Phase 4
-
IPACK on Early Pain Scores After ACL Reconstruction
RECRUITING · Phase 4
-
Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain
RECRUITING · Phase 4
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02397668 · 78 participants · NA
CorMatrix Cor TRICUSPID ECM Valve Replacement Study
- NCT03321656 · 78 participants · Phase 2
Impact of Envarsus XR® on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile
- NCT03687814 · 78 participants · NA
Low FODMAP Plus PEG 3350 for the Treatment of Patients with Irritable Bowel Syndrome-Constipation
- NCT04018872 · 78 participants · Phase 2
Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI