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NCT03790358 · ClinicalTrials.gov registry record · Phase 1
Mood Effects of Serotonin Agonists
A Phase 1 study, sponsored by University of Chicago.
- Completed
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
NCT03790358: Completed Phase 1 study, sponsored by University of Chicago.
NCT03790358 is a Phase 1 study that has completed, run by University of Chicago. The registered enrollment target is 80 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03790358, a Phase 1 study, has completed, sponsored by University of Chicago.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
Study Summary
The purpose of this study is to determine the effects of very low doses of serotonergic agonists on depressed mood in human volunteers.
Primary Outcome
The POMS measures individuals' mood states. This is a validated scale to measure positive and negative mood states. The POMS contains 30 items and assesses six identified mood factors: Tension-Anxiety, Depression-Ejection, Anger- Hostility, Vigor-Activity, Fatigue-Inertia, and Confusion-Bewilderment. Scoring of the instrument provides a global score of 0 to 120 or individual domain scores. Lower scores indicate better mood state. The POMS brief form is a simple self-rating instrument.
Interventions
- DRUG Lysergic Acid Diethylamide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2018-05-01 |
| Est. Completion | 2023-01-27 |
| Phase | Phase 1 |
What the finished NCT03790358 record still lists
NCT03790358 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% higher).
The record links to 0 conditions, and to 1 intervention - of which Lysergic Acid Diethylamide is the first listed.
NCT03790358 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03790358 about?
NCT03790358 is a clinical study titled "Mood Effects of Serotonin Agonists". The purpose of this study is to determine the effects of very low doses of serotonergic agonists on depressed mood in human volunteers.
What is the current status of trial NCT03790358?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2018-05-01. Estimated completion is 2023-01-27.
What interventions are being tested in trial NCT03790358?
The interventions under investigation include: Lysergic Acid Diethylamide (DRUG).
Who is sponsoring clinical trial NCT03790358?
This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03790358's enrollment target sits among peer trials
80 672nd of 2000 higher than 1,305 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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