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NCT03775577 · ClinicalTrials.gov registry record

Exercise Intolerance in Heart Failure

A clinical trial of Heart Failure With Normal Ejection Fraction, sponsored by Johns Hopkins University.

Recruiting
Registry status
130
Enrollment target
1
Study location

NCT03775577: Recruiting study of Heart Failure With Normal Ejection Fraction, sponsored by Johns Hopkins University.

NCT03775577 is a study of Heart Failure With Normal Ejection Fraction that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 130 participants, below the 627-participant average among 10 other Heart Failure With Normal Ejection Fraction trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03775577, a study of Heart Failure With Normal Ejection Fraction, is actively recruiting participants, sponsored by Johns Hopkins University.

RECRUITING
Registry status
130 participants
Enrollment target
1
Study location

Study Summary

The investigators are studying whether metabolic abnormalities in cardiac and skeletal muscle in patients with heart failure with preserved ejection fraction (HFpEF) are associated with debilitating exercise intolerance.

Primary Outcome

Maximal oxidative capacity of leg muscle measured by 31P Magnetic Resonance Spectroscopy (MRS)

Study Locations (1)

Maryland

  • Johns Hopkins Hospital - Baltimore

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2017-04-01
Est. Completion 2027-08
Johns Hopkins University

1,448 total trials

What NCT03775577 shows while recruiting

NCT03775577 is an observational study that tracks outcomes without assigning an intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 627-participant average among 10 other Heart Failure With Normal Ejection Fraction trials with a reported enrollment target (79% lower).

The record links to 1 condition, with Heart Failure With Normal Ejection Fraction appearing as the primary indexed condition, and to 0 interventions.

NCT03775577 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT03775577 about?

NCT03775577 is a clinical study titled "Exercise Intolerance in Heart Failure". The investigators are studying whether metabolic abnormalities in cardiac and skeletal muscle in patients with heart failure with preserved ejection fraction (HFpEF) are associated with debilitating exercise intolerance.

What is the current status of trial NCT03775577?

This trial is currently recruiting. The enrollment target is 130 participants. The study started on 2017-04-01. Estimated completion is 2027-08.

What conditions does trial NCT03775577 study?

This clinical trial studies the following conditions: Heart Failure With Normal Ejection Fraction.

Who is sponsoring clinical trial NCT03775577?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03775577 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Heart Failure With Normal Ejection Fraction

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03775577's enrollment target sits among peer trials

130 5th of 10 higher than 6 of 10 other Heart Failure With Normal Ejection Fraction trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Heart Failure With Normal Ejection Fraction trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03775577, the US trial registry maintained by the National Library of Medicine. NCT03775577 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.