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NCT03768063 · ClinicalTrials.gov registry record · Phase 3

A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study

A Phase 3 study of Cancer, sponsored by Hoffmann-La Roche.

Active
Registry status
Phase 3
Development phase
1,000
Enrollment target
20
Study locations

NCT03768063: Active Phase 3 study of Cancer, sponsored by Hoffmann-La Roche.

NCT03768063 is a Phase 3 study of Cancer that is active but no longer recruiting, run by Hoffmann-La Roche. The registered enrollment target is 1,000 participants, below the 3,489-participant average among 615 other Cancer trials with a reported enrollment target (71% lower). The trial reports 20 study locations across 14 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03768063, a Phase 3 study of Cancer, is active but no longer recruiting, sponsored by Hoffmann-La Roche.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
1,000 participants
Enrollment target
20
Study locations

Study Summary

This is an open-label, multicenter, extension study. Patients who are receiving clinical benefit from atezolizumab monotherapy or atezolizumab in combination with other agent(s) or combination/comparator agent(s) during participation in a Genentech or Roche-sponsored study (the parent study), who are eligible to continue treatment and who do not have access to the study treatment locally, may continue to receive study treatment in this extension study following roll-over from the parent study.

Conditions Studied

Interventions

  • DRUG Bevacizumab
  • DRUG Atezolizumab
  • DRUG Vemurafenib
  • DRUG Alectinib
  • DRUG Cobimetinib

Study Locations (20)

Other

  • Institut Jules Bordet - Brussels
  • UZ Brussel - Brussels
  • Multiprofile Hospital for Active Treatment Central Onco Hospital OOD - Plovdiv
  • Pontificia Universidad Catolica de Chile - Santiago
  • Masaryk?v onkologický ústav - Brno
  • Rigshospitalet - København Ø

Massachusetts

  • Massachusetts General Hospital - Boston
  • Beth Israel Deaconess Medical Center - Boston

Colorado

  • University of Colorado Cancer Center - Aurora

Connecticut

  • Yale University School Of Medicine - Trumbull

Florida

  • Advent Health Orlando - Maitland

North Carolina

  • Carolina BioOncology Institute, PLCC - Huntersville

Pennsylvania

  • St. Luke's Cancer Care Associates - Bethlehem

Texas

  • University of Texas Health Sciences Center in San Antonio - San Antonio

Trial Details

FieldValue
Enrollment Target 1,000 participants
Start Date 2019-02-28
Est. Completion 2028-07-05
Phase Phase 3
Hoffmann-La Roche

909 total trials

What the registry record for NCT03768063 still lists

NCT03768063 is an interventional study that assigns participants to a tested intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, below the 3,489-participant average among 615 other Cancer trials with a reported enrollment target (71% lower).

The record links to 1 condition, with Cancer appearing as the primary indexed condition, and to 5 interventions - of which Bevacizumab is the first listed.

NCT03768063 names 20 study sites across 14 states, led by Other, Massachusetts, Colorado.

Frequently Asked Questions

What is clinical trial NCT03768063 about?

NCT03768063 is a clinical study titled "A Study in Patients Previously Enrolled in a Genentech and/or F. Hoffmann-La Roche Ltd Sponsored Atezolizumab Study". This is an open-label, multicenter, extension study. Patients who are receiving clinical benefit from atezolizumab monotherapy or atezolizumab in combination with other agent(s) or combination/comparator agent(s) during participation in a Genentech or Roche-sponsored study (the parent study), who ar...

What is the current status of trial NCT03768063?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 1,000 participants. The study started on 2019-02-28. Estimated completion is 2028-07-05.

What conditions does trial NCT03768063 study?

This clinical trial studies the following conditions: Cancer.

What interventions are being tested in trial NCT03768063?

The interventions under investigation include: Bevacizumab (DRUG), Atezolizumab (DRUG), Vemurafenib (DRUG), Alectinib (DRUG), Cobimetinib (DRUG).

Who is sponsoring clinical trial NCT03768063?

This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03768063 being conducted?

This trial has 20 study locations across Colorado, Connecticut, Florida, Massachusetts, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03768063's enrollment target sits among peer trials

1,000 80th of 615 higher than 531 of 615 other Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03768063, the US trial registry maintained by the National Library of Medicine. NCT03768063 (large enrollment · wide site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.