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NCT03762915 · ClinicalTrials.gov registry record · Phase 4

Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres, 1 mg

A Phase 4 study of Biomarkers and SRP, sponsored by University of Minnesota.

Completed
Registry status
Phase 4
Development phase
70
Enrollment target
1
Study location

NCT03762915 is a Phase 4 study of Biomarkers and SRP that has completed, run by University of Minnesota. The registered enrollment target is 70 participants, below the 738-participant average among 5 other Biomarkers trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03762915, a Phase 4 study of Biomarkers and SRP, has completed, sponsored by University of Minnesota.

COMPLETED
Registry status
Phase 4
Development phase
70 participants
Enrollment target
1
Study location

Study Summary

The primary goal of this study is to investigate the qualitative and quantitative effects of scaling and root planing (SRP) with and without minocycline HCL microspheres, 1 mg on periodontal pathogens and overall bacterial load. A randomized controlled clinical trial of a control (SRP) group and an experimental (SRP with minocycline HCl microspheres, 1 mg) group is planned. Specific Aim 1: Evaluate the cumulative oral periodontal bacterial burden in both control and test groups over a six month period. Specific Aim 2: Assess gingival crevicular fluid (GCF) and serum biomarkers of inflammation.

Interventions

  • DRUG minocycline HCl microspheres

Study Locations (1)

Minnesota

  • University of Minnesota - Minneapolis

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2019-05-20
Est. Completion 2022-04-01
Phase Phase 4

Sponsor

University of Minnesota

966 total trials

What the Registry Record Tells You About NCT03762915

The ClinicalTrials.gov registry entry for NCT03762915 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 738-participant average among 5 other Biomarkers trials with a reported enrollment target (91% lower). The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Biomarkers appearing as the primary indexed condition, and to 1 intervention - of which minocycline HCl microspheres is the first listed.

NCT03762915 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT03762915 about?

NCT03762915 is a clinical study titled "Scaling and Root Planing (SRP) With and Without Minocycline HCl Microspheres, 1 mg". The primary goal of this study is to investigate the qualitative and quantitative effects of scaling and root planing (SRP) with and without minocycline HCL microspheres, 1 mg on periodontal pathogens and overall bacterial load. A randomized controlled clinical trial of a control (SRP) group and an...

What is the current status of trial NCT03762915?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 70 participants. The study started on 2019-05-20. Estimated completion is 2022-04-01.

What conditions does trial NCT03762915 study?

This clinical trial studies the following conditions: Biomarkers, SRP, Minocycline HCl Microspheres.

What interventions are being tested in trial NCT03762915?

The interventions under investigation include: minocycline HCl microspheres (DRUG).

Who is sponsoring clinical trial NCT03762915?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03762915 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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