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NCT03717922 · ClinicalTrials.gov registry record · NA
Low Intensity Focused Ultrasound for Learning and Memory and Emotion Regulation
A NA study, sponsored by University of California, Los Angeles.
- Completed
- Registry status
- NA
- Development phase
- 21
- Enrollment target
NCT03717922: Completed NA study, sponsored by University of California, Los Angeles.
NCT03717922 is a NA study that has completed, run by University of California, Los Angeles. The registered enrollment target is 21 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03717922, a NA study, has completed, sponsored by University of California, Los Angeles.
- COMPLETED
- Registry status
- NA
- Development phase
- 21 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to investigate the impact of low intensity focused ultrasound pulsation (LIFUP) to two different brain regions, the amygdala and entorhinal cortex, in older adults. The main questions it aims to answer are: 1. Will LIFUP change brain activity in the targeted regions? 2. Will LIFUP to the amygdala have an impact on anxiety and emotion regulation? 3. Will LIFUP to the entorhinal cortex have an impact on memory performance? Participants will complete two in-person visits including neuropsychological testing, MRI of the brain, and LIFUP to the brain.
Primary Outcome
The Rey Auditory Verbal Learning Task is an assessment of verbal memory in which a list of 15 words is presented 5 times and participants are asked to repeat all the words they can remember immediately after each list presentation. This is followed by presentation and recall of an interference list. Immediately after the interference trial, the participant is asked to recall the original list. Then, 20 minutes later, they are asked to recall the original list again (delayed recall). "Learning T
Interventions
- DEVICE Low Intensity Focused Ultrasound Pulsation to Amygdala
- DEVICE Low Intensity Focused Ultrasound Pulsation to Entorhinal Cortex
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2019-06-28 |
| Est. Completion | 2022-12-20 |
| Phase | NA |
What the finished NCT03717922 record still lists
NCT03717922 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Low Intensity Focused Ultrasound Pulsation to Amygdala is the first listed.
NCT03717922 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03717922 about?
NCT03717922 is a clinical study titled "Low Intensity Focused Ultrasound for Learning and Memory and Emotion Regulation". The goal of this clinical trial is to investigate the impact of low intensity focused ultrasound pulsation (LIFUP) to two different brain regions, the amygdala and entorhinal cortex, in older adults. The main questions it aims to answer are: 1. Will LIFUP change brain activity in the targeted regio...
What is the current status of trial NCT03717922?
This trial is currently completed. It is a NA study. The enrollment target is 21 participants. The study started on 2019-06-28. Estimated completion is 2022-12-20.
What interventions are being tested in trial NCT03717922?
The interventions under investigation include: Low Intensity Focused Ultrasound Pulsation to Amygdala (DEVICE), Low Intensity Focused Ultrasound Pulsation to Entorhinal Cortex (DEVICE).
Who is sponsoring clinical trial NCT03717922?
This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03717922's enrollment target sits among peer trials
21 1762nd of 2000 higher than 233 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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