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NCT03709784 · ClinicalTrials.gov registry record

Spinraza in Adult Spinal Muscular Atrophy

A clinical trial of Spinal Muscular Atrophy and Spinal Muscular Atrophy Type 3, sponsored by Washington University School of Medicine.

Active
Registry status
148
Enrollment target
11
Study locations

NCT03709784 is a study of Spinal Muscular Atrophy and Spinal Muscular Atrophy Type 3 that is active but no longer recruiting, run by Washington University School of Medicine. The registered enrollment target is 148 participants, above the 102-participant average among 22 other Spinal Muscular Atrophy trials with a reported enrollment target (45% higher). The trial reports 11 study locations across 11 states.

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The verdict

NCT03709784, a study of Spinal Muscular Atrophy and Spinal Muscular Atrophy Type 3, is active but no longer recruiting, sponsored by Washington University School of Medicine.

ACTIVE NOT RECRUITING
Registry status
148 participants
Enrollment target
11
Study locations

Study Summary

This is a longitudinal, observational study of adult patients with genetically confirmed chromosome 5q SMA to examine the safety, tolerability, and effectiveness of SPINRAZA® (nusinersen) for up to 30 months.

Interventions

  • DRUG Observational study to examine safety, tolerability, and effectiveness of SPINRAZA® prescribed as part of standard of care
  • OTHER One time survey

Study Locations (11)

Arizona

  • Barrow Neurological Institute - Phoenix

District of Columbia

  • Georgetown University - Washington D.C.

Maryland

  • Johns Hopkins - Baltimore

Massachusetts

  • Massachusetts General Hospital-Harvard University - Boston

Michigan

  • Memorial Healthcare - Owosso

Missouri

  • Washington University School of Medicine - St Louis

New York

  • New York University School of Medicine - New York

Texas

  • Houston Methodist Neurological Institute - Houston

Trial Details

FieldValue
Enrollment Target 148 participants
Start Date 2018-08-16
Est. Completion 2025-01-01

What the Registry Record Tells You About NCT03709784

The ClinicalTrials.gov registry entry for NCT03709784 describes a study currently listed as active not recruiting, categorized as an unspecified phase. The registered enrollment target is 148 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 102-participant average among 22 other Spinal Muscular Atrophy trials with a reported enrollment target (45% higher). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Spinal Muscular Atrophy appearing as the primary indexed condition, and to 2 interventions - of which Observational study to examine safety, tolerability, and effectiveness of SPINRAZA® prescribed as part of standard of care is the first listed.

NCT03709784 reports 11 study locations spanning 11 distinct geographic areas - top geographies include Arizona, District of Columbia, Maryland.

Frequently Asked Questions

What is clinical trial NCT03709784 about?

NCT03709784 is a clinical study titled "Spinraza in Adult Spinal Muscular Atrophy". This is a longitudinal, observational study of adult patients with genetically confirmed chromosome 5q SMA to examine the safety, tolerability, and effectiveness of SPINRAZA® (nusinersen) for up to 30 months.

What is the current status of trial NCT03709784?

This trial is currently active not recruiting. The enrollment target is 148 participants. The study started on 2018-08-16. Estimated completion is 2025-01-01.

What conditions does trial NCT03709784 study?

This clinical trial studies the following conditions: Spinal Muscular Atrophy, Spinal Muscular Atrophy Type 3, Spinal Muscular Atrophy Type II.

What interventions are being tested in trial NCT03709784?

The interventions under investigation include: Observational study to examine safety, tolerability, and effectiveness of SPINRAZA® prescribed as part of standard of care (DRUG), One time survey (OTHER).

Who is sponsoring clinical trial NCT03709784?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03709784 being conducted?

This trial has 11 study locations across Arizona, District of Columbia, Maryland, Massachusetts, Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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