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NCT03694002 · ClinicalTrials.gov registry record · Phase 2

Carboplatin and Paclitaxel With or Without Ramucirumab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Thymic Cancer That Cannot Be Removed by Surgery

A Phase 2 study of Unresectable Thymic Carcinoma and Locally Advanced Thymic Carcinoma, sponsored by SWOG Cancer Research Network.

Completed
Registry status
Phase 2
Development phase
21
Enrollment target
20
Study locations

NCT03694002 is a Phase 2 study of Unresectable Thymic Carcinoma and Locally Advanced Thymic Carcinoma that has completed, run by SWOG Cancer Research Network. The registered enrollment target is 21 participants. The trial reports 20 study locations across 4 states.

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The verdict

NCT03694002, a Phase 2 study of Unresectable Thymic Carcinoma and Locally Advanced Thymic Carcinoma, has completed, sponsored by SWOG Cancer Research Network.

COMPLETED
Registry status
Phase 2
Development phase
21 participants
Enrollment target
20
Study locations

Study Summary

This randomized phase II trial studies how well carboplatin and paclitaxel with or without ramucirumab work in treating patients with thymic cancer that has spread to other places in the body, has come back, or cannot be removed by surgery. Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Monoclonal antibodies, such as ramucirumab, may interfere with the ability of tumor cells to grow and spread. It is not yet known if giving carboplatin and paclitaxel with or without ramucirumab will work better in treating patients with thymic cancer.

Interventions

  • DRUG Carboplatin
  • DRUG Paclitaxel
  • BIOLOGICAL Ramucirumab

Study Locations (20)

California

  • Mission Hope Medical Oncology - Arroyo Grande - Arroyo Grande
  • PCR Oncology - Arroyo Grande
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center - Burbank
  • City of Hope Comprehensive Cancer Center - Duarte
  • City of Hope Antelope Valley - Lancaster
  • Fremont - Rideout Cancer Center - Marysville
  • City of Hope Mission Hills - Mission Hills
  • University of California Davis Comprehensive Cancer Center - Sacramento
  • Mission Hope Medical Oncology - Santa Maria - Santa Maria
  • City of Hope South Pasadena - South Pasadena

Alaska

  • Anchorage Associates in Radiation Medicine - Anchorage
  • Anchorage Radiation Therapy Center - Anchorage
  • Alaska Breast Care and Surgery LLC - Anchorage
  • Alaska Oncology and Hematology LLC - Anchorage
  • Alaska Women's Cancer Care - Anchorage
  • Anchorage Oncology Centre - Anchorage
  • Katmai Oncology Group - Anchorage
  • Providence Alaska Medical Center - Anchorage

Arizona

  • Kingman Regional Medical Center - Kingman

Arkansas

  • CHI Saint Vincent Cancer Center Hot Springs - Hot Springs

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2019-03-20
Est. Completion 2025-03-03
Phase Phase 2

Sponsor

SWOG Cancer Research Network

270 total trials

What the Registry Record Tells You About NCT03694002

The ClinicalTrials.gov registry entry for NCT03694002 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is SWOG Cancer Research Network, which has 270 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Unresectable Thymic Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Carboplatin is the first listed.

NCT03694002 reports 20 study locations spanning 4 distinct geographic areas - top geographies include California, Alaska, Arizona.

Frequently Asked Questions

What is clinical trial NCT03694002 about?

NCT03694002 is a clinical study titled "Carboplatin and Paclitaxel With or Without Ramucirumab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Thymic Cancer That Cannot Be Removed by Surgery". This randomized phase II trial studies how well carboplatin and paclitaxel with or without ramucirumab work in treating patients with thymic cancer that has spread to other places in the body, has come back, or cannot be removed by surgery. Drugs used in chemotherapy, such as carboplatin and paclita...

What is the current status of trial NCT03694002?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 21 participants. The study started on 2019-03-20. Estimated completion is 2025-03-03.

What conditions does trial NCT03694002 study?

This clinical trial studies the following conditions: Unresectable Thymic Carcinoma, Locally Advanced Thymic Carcinoma, Metastatic Thymic Carcinoma, Recurrent Thymic Carcinoma.

What interventions are being tested in trial NCT03694002?

The interventions under investigation include: Carboplatin (DRUG), Paclitaxel (DRUG), Ramucirumab (BIOLOGICAL).

Who is sponsoring clinical trial NCT03694002?

This trial is sponsored by SWOG Cancer Research Network, which has 270 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03694002 being conducted?

This trial has 20 study locations across Alaska, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.