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NCT03688126 · ClinicalTrials.gov registry record · NA
U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk
A NA study, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- NA
- Development phase
- 2,000
- Enrollment target
NCT03688126: Completed NA study, sponsored by Wake Forest University Health Sciences.
NCT03688126 is a NA study that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 2,000 participants, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (42% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03688126, a NA study, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- NA
- Development phase
- 2,000 participants
- Enrollment target
Study Summary
The purpose of this research study is to see if lifestyle changes can protect memory and thinking (cognition) as we age. A recent study in Finland found that a combination of physical and cognitive exercise, diet, and social activity protected cognitive function in healthy older adults who were at increased risk of significant memory loss. So far no medications can rival this positive outcome. The point of POINTER is to test if lifestyle change can also protect against memory loss in Americans.
Primary Outcome
Global cognitive function will be obtained from a composite score derived from subtest scores on the POINTER modified Neuropsychological Test Battery (PmNTB) that includes: Free and Cued Selective Reminding Test, Story Recall, Visual Paired Associates, Number Span, Word Fluency, Trail-Making Test, and Digit Symbol Substitution Test. Scores from each individual test will be converted to z-scores that typically range from -3 to 3, with higher scores reflecting better performance, and averaged to f
Interventions
- BEHAVIORAL Self-Guided Lifestyle Intervention
- BEHAVIORAL Structured Lifestyle Intervention
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,000 participants |
| Start Date | 2019-01-08 |
| Est. Completion | 2025-05-16 |
| Phase | NA |
What the finished NCT03688126 record still lists
NCT03688126 is an interventional study that assigns participants to a tested intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus, above the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (42% higher).
The record links to 0 conditions, and to 2 interventions - of which Self-Guided Lifestyle Intervention is the first listed.
NCT03688126 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03688126 about?
NCT03688126 is a clinical study titled "U.S. Study to Protect Brain Health Through Lifestyle Intervention to Reduce Risk". The purpose of this research study is to see if lifestyle changes can protect memory and thinking (cognition) as we age. A recent study in Finland found that a combination of physical and cognitive exercise, diet, and social activity protected cognitive function in healthy older adults who were at i...
What is the current status of trial NCT03688126?
This trial is currently completed. It is a NA study. The enrollment target is 2,000 participants. The study started on 2019-01-08. Estimated completion is 2025-05-16.
What interventions are being tested in trial NCT03688126?
The interventions under investigation include: Self-Guided Lifestyle Intervention (BEHAVIORAL), Structured Lifestyle Intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT03688126?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03688126's enrollment target sits among peer trials
2,000 52nd of 2000 higher than 1,947 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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