Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03677440 · ClinicalTrials.gov registry record · NA
Exercise Training Effects on Cognition and Brain Function in Multiple Sclerosis: Project EXACT
A NA study of Multiple Sclerosis and Cognitive Impairment, sponsored by Kessler Foundation.
- Completed
- Registry status
- NA
- Development phase
- 43
- Enrollment target
- 1
- Study location
NCT03677440 is a NA study of Multiple Sclerosis and Cognitive Impairment that has completed, run by Kessler Foundation. The registered enrollment target is 43 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.
The verdict
NCT03677440, a NA study of Multiple Sclerosis and Cognitive Impairment, has completed, sponsored by Kessler Foundation.
- COMPLETED
- Registry status
- NA
- Development phase
- 43 participants
- Enrollment target
- 1
- Study location
Study Summary
Cognitive impairment is highly prevalent, poorly-managed, and disabling in persons with MS and exercise training might represent a promising approach to manage this symptom of the disease. The proposed study aims to examine the effects of 3-months of supervised, progressive (both intensity and duration) treadmill walking exercise training (designed based on pilot work and American College of Sports Medicine guidelines) compared with an active control condition (i.e., stretching-and-toning activities) on cognitive processing speed and functional MRI outcomes in 88 cognitively-impaired persons with MS. This study is critical for providing evidence supporting treadmill walking exercise training as a behavioral approach for managing slowed cognitive processing speed (i.e., the most common MS-related cognitive impairment) and improving brain health in persons with MS.
Conditions Studied
Interventions
- BEHAVIORAL Treadmill Walking Exercise Training
- BEHAVIORAL Stretching-and-Toning Exercise Training
Study Locations (1)
New Jersey
- Kessler Foundation - West Orange
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 43 participants |
| Start Date | 2019-02-05 |
| Est. Completion | 2024-12-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03677440
The ClinicalTrials.gov registry entry for NCT03677440 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (93% lower). The listed sponsor is Kessler Foundation, which has 104 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Multiple Sclerosis appearing as the primary indexed condition, and to 2 interventions - of which Treadmill Walking Exercise Training is the first listed.
NCT03677440 reports 1 study location spanning 1 distinct geographic area - top geographies include New Jersey.
Frequently Asked Questions
What is clinical trial NCT03677440 about?
NCT03677440 is a clinical study titled "Exercise Training Effects on Cognition and Brain Function in Multiple Sclerosis: Project EXACT". Cognitive impairment is highly prevalent, poorly-managed, and disabling in persons with MS and exercise training might represent a promising approach to manage this symptom of the disease. The proposed study aims to examine the effects of 3-months of supervised, progressive (both intensity and durat...
What is the current status of trial NCT03677440?
This trial is currently completed. It is a NA study. The enrollment target is 43 participants. The study started on 2019-02-05. Estimated completion is 2024-12-31.
What conditions does trial NCT03677440 study?
This clinical trial studies the following conditions: Multiple Sclerosis, Cognitive Impairment.
What interventions are being tested in trial NCT03677440?
The interventions under investigation include: Treadmill Walking Exercise Training (BEHAVIORAL), Stretching-and-Toning Exercise Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT03677440?
This trial is sponsored by Kessler Foundation, which has 104 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03677440 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Sclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Prepare the Mind: Can Coaching in Goal-directed Behaviour Increase the Success of Cognitive Rehabilitation in People With MS?
RECRUITING · NA
-
Incremental Vestibulo-ocular Reflex Adaptation as a Novel Treatment for Dizziness in People With Multiple Sclerosis
RECRUITING · NA
-
Intermittent Hypoxia in Persons With Multiple Sclerosis
RECRUITING · NA
-
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
RECRUITING · NA
-
Central Vein Sign in Multiple Sclerosis Extension Study
RECRUITING · NA
-
Effects of Torso Weighting on Muscle Activation During Balance Tests in Individuals With and Without Multiple Sclerosis
RECRUITING · NA
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.